Precursor lymphoblastic lymphoma/leukemia
MONDO:0003538A neoplasm of immature malignant lymphocytes (lymphoblasts) committed to the B-cell or T-cell lineage. Neoplasms involving the bone marrow and the peripheral blood are called precursor lymphoblastic leukemias or acute lymphoblastic leukemias. Neoplasms involving primarily lymph nodes or extranodal sites are called lymphoblastic lymphomas. -- 2003
Also known as: precursor lymphoblastic leukemia/lymphoma, precursor lymphoblastic lymphoma/leukemia, precursor lymphoid neoplasm
3162 clinical trials for this condition and its sub-types, 12 tagged with Precursor lymphoblastic lymphoma/leukemia itself.
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Sub-types of Precursor lymphoblastic lymphoma/leukemia
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Acute lymphoblastic leukemia 508 trials · 1,319 incl. sub-types
12 sub-types
- B-cell chronic lymphocytic leukemia 509 trials · 538 incl. sub-types Sub-types →
- B-cell acute lymphoblastic leukemia 245 trials · 259 incl. sub-types Sub-types →
- Childhood acute lymphoblastic leukemia 96 trials · 136 incl. sub-types Sub-types →
- Precursor B-cell acute lymphoblastic leukemia 68 trials · 113 incl. sub-types Sub-types →
- T-cell acute lymphoblastic leukemia 75 trials · 104 incl. sub-types Sub-types →
- Acute biphenotypic leukemia 88 trials · 91 incl. sub-types Sub-types →
- Adult acute lymphoblastic leukemia 43 trials · 54 incl. sub-types Sub-types →
- Prolymphocytic leukemia 20 trials · 38 incl. sub-types Sub-types →
- Plasma cell leukemia 32 trials
- Lymphoblastic leukemia, acute, with lymphomatous features 7 trials
- Precursor T-cell acute lymphoblastic leukemia 4 trials
- Null-cell leukemia 0 trials
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Lymphoblastic lymphoma 78 trials · 104 incl. sub-types
2 sub-types
- T-lymphoblastic lymphoma 32 trials
- T-cell childhood lymphoblastic lymphoma 4 trials
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T lymphoblastic leukemia/lymphoma 18 trials · 100 incl. sub-types
5 sub-types
- T-lymphoblastic lymphoma 32 trials
- Refractory precursor T-lymphoblastic lymphoma/leukemia 31 trials
- T-cell prolymphocytic leukemia 17 trials
- Childhood precursor T-lymphoblastic lymphoma/leukemia 0 trials · 13 incl. sub-types Sub-types →
- Aggressive NK-cell leukemia 11 trials
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B-lymphoblastic leukemia/lymphoma with recurrent genetic abnormality 0 trials · 59 incl. sub-types
6 sub-types
- B-lymphoblastic leukemia/lymphoma with t(9;22)(q34.1;q11.2) 51 trials
- B-lymphoblastic leukemia/lymphoma with t(v;11q23.3) 8 trials
- B-lymphoblastic leukemia/lymphoma with hypodiploidy 3 trials
- B-lymphoblastic leukemia/lymphoma with hyperdiploidy 0 trials
- B-lymphoblastic leukemia/lymphoma with t(12;21)(p13.2;q22.1) 0 trials
- B-lymphoblastic leukemia/lymphoma with t(5;14)(q31.1;q32.3) 0 trials
Most studied deeper sub-types
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Experimental drug TURALIO takes on tough childhood cancers in early trial
Disease control Recruiting nowThis early-phase study tests the drug TURALIO (pexidartinib) in people aged 3 to 35 whose cancer has not responded to standard treatments. The goal is to find a safe dose and see if it can shrink tumors or control leukemia. Participants take a daily capsule for up to 2 years, wit…
Phase 1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Aug 26, 2026 00:00 UTC
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New combo therapy aims to boost leukemia remission with fewer side effects
Disease control Recruiting nowThis study is testing a new treatment approach for adults newly diagnosed with a specific type of leukemia (Ph-negative B-cell acute lymphoblastic leukemia). The treatment combines low-dose chemotherapy with several targeted immunotherapy drugs. The goal is to see if this gentler…
Phase 2 • Sponsor: Institute of Hematology & Blood Diseases Hospital, China • Aim: Disease control
Last updated Jun 27, 2026 08:04 UTC
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Engineered immune cells take on tough leukemia in kids
Disease control Recruiting nowThis early-stage trial is testing a type of immunotherapy called CAR T cells in children, adolescents, and young adults with acute lymphoblastic leukemia that has come back or not responded to standard treatments. The therapy involves taking the patient's own immune cells or dono…
Phase 1 • Sponsor: Instituto de Investigación Hospital Universitario La Paz • Aim: Disease control
Last updated Jun 27, 2026 07:51 UTC
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New combo therapy offers hope for kids with tough leukemia
Disease control Recruiting nowThis study tests a new combination of drugs for children and young adults whose leukemia or lymphoma has returned or not responded to treatment. The drugs include trametinib (a targeted therapy) plus standard chemotherapy. The goal is to find the safest dose and see if the combin…
Phase 1/2 • Sponsor: Princess Maxima Center for Pediatric Oncology • Aim: Disease control
Last updated Jun 26, 2026 18:46 UTC
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New hope for kids with tough blood cancers: drug cocktail trial launches
Disease control Recruiting nowThis study tests a combination of two targeted drugs (ruxolitinib and venetoclax) plus standard chemotherapy in children and young adults up to age 21 whose leukemia or lymphoma has returned or not responded to treatment. The goal is to find the safest dose and see how many patie…
Phase 1/2 • Sponsor: Princess Maxima Center for Pediatric Oncology • Aim: Disease control
Last updated Jun 26, 2026 17:34 UTC
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Healing harmonies: music therapy aims to ease stem cell transplant recovery
Symptom relief Recruiting nowThis study tests an online music therapy program that combines mindfulness and music to help people recovering from stem cell transplants for blood cancers. Researchers want to see if it can improve quality of life, reduce pain, fatigue, anxiety, and depression, and possibly spee…
Sponsor: University of Miami • Aim: Symptom relief
Last updated Aug 15, 2026 00:00 UTC
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Virtual play therapy aims to boost motor skills and social life in young leukemia survivors
Symptom relief Recruiting nowThis study tests a 12-week virtual buddy-movement therapy for children aged 5 to 12 who have finished treatment for acute lymphoblastic leukemia. The program pairs each child with a healthy buddy for twice-weekly movement sessions designed to improve motor skills, coordination, a…
Sponsor: Comenius University • Aim: Symptom relief
Last updated Jun 27, 2026 12:30 UTC
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Scientists collect samples to unlock secrets of lymphoid cancers
Knowledge-focused Recruiting nowThis study collects blood, urine, bone marrow, and tissue samples from over 1,200 adults with lymphoid cancers or precancerous conditions. The goal is to help researchers better understand cancer biology, which may lead to new methods for diagnosing or treating these diseases. No…
Sponsor: National Cancer Institute (NCI) • Aim: Knowledge-focused
Last updated Sep 10, 2026 00:00 UTC