Pneumocystis infectious disease
MONDO:0005923Infections with species in the genus pneumocystis, a fungus causing interstitial plasma cell pneumonia (pneumonia, pneumocystis) and other infections in humans and other mammals. Immunocompromised patients, especially those with aids, are particularly susceptible to these infections. Extrapulmonary sites are rare but seen occasionally.
Also known as: Pneumocystis infection, infections, Pneumocystis
20 clinical trials for this condition and its sub-types, 4 tagged with Pneumocystis infectious disease itself.
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Browse by category →Sub-types of Pneumocystis infectious disease
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Pneumocystosis 19 trials
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Could a lower dose of a common antibiotic be safer and just as effective for a deadly pneumonia?
Disease control Not yet recruitingThis study looks at whether a lower dose of the antibiotic TMP-SMX works as well as the standard dose for treating a serious lung infection called Pneumocystis pneumonia (PCP) in people who do not have HIV. The standard dose often causes side effects in more than half of patients…
Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang University • Aim: Disease control
Last updated Jul 16, 2026 00:00 UTC
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Can a cancer drug wake up immune cells to beat HIV-Related infections?
Disease control Not yet recruitingThis study tests a drug called Sintilimab, which is normally used for cancer, to see if it can help people with HIV who have infections that won't go away with standard treatment. The drug works by 'waking up' exhausted immune cells. Fifty adults with HIV and a hard-to-treat infe…
Phase 1/2 • Sponsor: Shanghai Public Health Clinical Center • Aim: Disease control
Last updated Jun 27, 2026 12:31 UTC
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New study seeks best backup plan for deadly pneumonia in immunocompromised patients
Disease control Not yet recruitingThis study looks at which second-choice treatment works best for a serious lung infection called PCP when the usual antibiotic cannot be used due to allergies, side effects, or failure. About 416 adults with weakened immune systems (from HIV, transplants, cancer, or other causes)…
Phase 4 • Sponsor: McGill University Health Centre/Research Institute of the McGill University Health Centre • Aim: Disease control
Last updated Jun 27, 2026 08:13 UTC
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Shorter steroid course for severe PCP? new trial aims to find out
Disease control Not yet recruitingThis study looks at how long steroids should be given to adults with severe Pneumocystis pneumonia (PCP), a serious lung infection common in people with weakened immune systems. About 416 participants who improve within 10 days will either stop steroids early or continue for 21 d…
Phase 4 • Sponsor: McGill University Health Centre/Research Institute of the McGill University Health Centre • Aim: Disease control
Last updated Jun 27, 2026 08:09 UTC
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Could steroids slash death rates from a rare pneumonia?
Disease control Not yet recruitingThis study tests whether adding corticosteroids (low or moderate dose) to standard care can reduce deaths from severe Pneumocystis pneumonia (PJP) in non-HIV patients in the ICU. PJP has a very high death rate of 60-80% in this group. The trial will compare two steroid doses agai…
Phase 3 • Sponsor: Qingyuan Zhan • Aim: Disease control
Last updated Jun 26, 2026 14:24 UTC
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Can steroids save lives in severe pneumonia? new trial aims to find out
Disease control Not yet recruitingThis trial tests whether low or moderate doses of the steroid methylprednisolone can reduce deaths in patients with severe community-acquired pneumonia. It will enroll 1500 ICU patients with pneumonia caused by adenovirus or Pneumocystis jirovecii. The study uses an adaptive desi…
Phase 2/3 • Sponsor: Qingyuan Zhan • Aim: Disease control
Last updated Jun 26, 2026 13:09 UTC
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Can a lower dose of antibiotics prevent pneumonia just as well after kidney transplant?
Prevention Not yet recruitingThis study tests whether a lower dose of the antibiotic TMP-SMX works as well as the standard dose to prevent a serious lung infection called PJP in people who have just had a kidney transplant. About 1,084 adult first-time kidney transplant recipients will take either a low or s…
Phase 4 • Sponsor: Anhui Provincial Hospital • Aim: Prevention
Last updated Jun 27, 2026 13:00 UTC
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Could a common steroid prevent a deadly complication in AIDS patients?
Prevention Not yet recruitingThis study tests whether a short course of the steroid prednisolone can prevent paradoxical immune reconstitution inflammatory syndrome (IRIS) in people with AIDS who have low CD4 counts and are starting HIV treatment. About 131 participants will receive either prednisolone or no…
Sponsor: Shanghai Public Health Clinical Center • Aim: Prevention
Last updated Jun 27, 2026 12:29 UTC