Pleural epithelioid mesothelioma
MONDO:0006378Malignant mesothelioma that arises from the pleura and is characterized by the presence of cells with epithelioid morphology. The epithelioid cells usually have eosinophilic cytoplasm, bland nuclei, and form tubulopapillary, microglandular, or sheet-like patterns.
Also known as: malignant epithelioid mesothelioma of pleura, pleura malignant epithelioid mesothelioma, pleural epithelioid mesothelioma
2769 clinical trials for this condition and its sub-types, 8 tagged with Pleural epithelioid mesothelioma itself.
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Immune booster shows promise against rare cancer
Disease control CompletedThis study tested a drug called pembrolizumab in 65 people with malignant mesothelioma, a rare cancer of the lining around the lungs or abdomen. The drug works by helping the immune system attack cancer cells. The goal was to see if it could shrink tumors or slow the disease, but…
Phase 2 • Sponsor: University of Chicago • Aim: Disease control
Last updated Jun 27, 2026 12:30 UTC
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Light therapy shows promise in tough mesothelioma trial
Disease control CompletedThis pilot study tested whether adding intrapleural photodynamic therapy (PDT) to standard surgery and chemotherapy is safe and feasible for patients with malignant pleural mesothelioma. Six participants received a light-sensitive drug followed by laser light inside the chest cav…
Phase 2 • Sponsor: University Hospital, Lille • Aim: Disease control
Last updated Jun 27, 2026 09:02 UTC
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Immunotherapy plus chemo shows promise in tough lung cancer
Disease control CompletedThis study tested whether adding the immunotherapy drug durvalumab to standard chemotherapy helps people with advanced pleural mesothelioma live longer. The trial included 214 adults whose cancer could not be removed by surgery. Participants received either the combination or a s…
Phase 3 • Sponsor: PrECOG, LLC. • Aim: Disease control
Last updated Jun 27, 2026 08:12 UTC