Pleomorphic rhabdomyosarcoma

MONDO:0017386

An aggressive malignant mesenchymal neoplasm with skeletal muscle differentiation, occurring in adults and rarely in children. The tumor is characterized by the presence of bizarre round, spindle, and polygonal cells. Clinical presentation includes a rapidly enlarging painful mass usually of the lower extremities.

Also known as: pleomorphic rhabdomyosarcoma

2827 clinical trials for this condition and its sub-types, 7 tagged with Pleomorphic rhabdomyosarcoma itself.

Follow this condition to get notified about new trials

Where it sits in the disease tree

Browse by category →

Part of

↑ Rhabdomyosarcoma (114)

Sub-types of Pleomorphic rhabdomyosarcoma

Adult pleomorphic rhabdomyosarcoma 0 trials
Childhood pleomorphic rhabdomyosarcoma 0 trials

Including sub-types (2827) Tagged with Pleomorphic rhabdomyosarcoma (7)

Trials to join now! 4 Not yet finished but already full! 1 Completed 2

Experimental combo aims to boost immune attack on sarcoma before surgery

Disease control Ongoing

This early-phase study tests the safety of combining two immunotherapy drugs—nivolumab and BO-112—given before surgery for soft tissue sarcoma that can be removed. About 14 adults with certain sarcoma types will receive these drugs to see if they help the immune system fight the …

Phase 1 • Sponsor: Jonsson Comprehensive Cancer Center • Aim: Disease control

Last updated Jun 27, 2026 11:00 UTC

Pleomorphic rhabdomyosarcoma

Where it sits in the disease tree

Experimental combo aims to boost immune attack on sarcoma before surgery