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Pleomorphic adenoma
MONDO:0008401A neoplasm characterized by the presence of benign epithelial and myoepithelial cells and a mesenchymal component that may contain mucoid, myxoid, cartilaginous, or osseous areas. It may be completely or partially encapsulated. It occurs in the parotid gland, submandibular gland, minor salivary glands in the oral cavity, upper respiratory tract, and nasal cavity and paranasal sinuses. It usually presents as a slow growing painless mass. Infrequently, patients may present with pain and facial palsy. It may recur after excision or transform to a malignant neoplasm (carcinoma ex pleomorphic adenoma).
Also known as: adenomas, salivary gland pleomorphic, somatic, pleomorphic adenoma, pleomorphic adenoma (morphologic abnormality), tumor, mixed, benign, Psa, Sgpa, mixed tumor of the salivary gland, mixed tumour of the salivary gland
1469 clinical trials for this condition and its sub-types, 12 tagged with Pleomorphic adenoma itself.
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Could a common diabetes drug protect PsA Patients' hearts?
Disease control CompletedThis pilot study tested whether adding metformin to standard care can slow the buildup of plaque in the carotid arteries of people with psoriatic arthritis (PsA) who do not have diabetes. Twenty-four participants with PsA and existing carotid plaque were randomly assigned to take…
Phase 4 • Sponsor: Chinese University of Hong Kong • Aim: Disease control
Last updated Jun 27, 2026 07:59 UTC
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Glow-in-the-Dark dye could help surgeons avoid nerves
Knowledge-focused CompletedThis small study tested whether injecting a fluorescent dye called fluorescein sodium helps surgeons see nerves during head and neck surgery. Eight adults having open head or neck surgery received the dye through an IV. Surgeons then rated how well the glowing nerves matched stan…
Phase 2 • Sponsor: Stanford University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:35 UTC
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New guidelines aim to make prostate cancer screening smarter, not just more frequent
Knowledge-focused CompletedThis study tested new guidelines for PSA screening to help doctors decide when to start and stop screening, how often to repeat it, and when to refer for biopsy. Researchers also provided patient navigation for men with elevated PSA levels. The goal was to see if these steps coul…
Sponsor: University of Illinois at Chicago • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:12 UTC
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Which prostate biopsy method is safer and better at finding cancer?
Knowledge-focused CompletedThis study compared two common methods for taking a prostate biopsy: one through the rectal wall and one through the skin between the scrotum and anus. 840 men who needed a biopsy for suspected prostate cancer were randomly assigned to one of the two methods. The goal was to see …
Sponsor: Albany Medical College • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:05 UTC