Pituitary gland disorder
MONDO:0003381A disease involving the pituitary gland.
Also known as: disease of pituitary gland, disease or disorder of pituitary gland, disorder of pituitary gland, pituitary gland disease, pituitary gland disease or disorder, pituitary gland disorder
175 clinical trials for this condition and its sub-types, 18 tagged with Pituitary gland disorder itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
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Sub-types of Pituitary gland disorder
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Pituitary tumor 23 trials · 83 incl. sub-types
9 sub-types
- Pituitary gland adenoma 34 trials · 67 incl. sub-types Sub-types →
- Functioning pituitary gland neoplasm 0 trials · 24 incl. sub-types Sub-types →
- Prolactin producing pituitary tumor 2 trials · 11 incl. sub-types Sub-types →
- Non-functioning pituitary gland neoplasm 0 trials · 9 incl. sub-types Sub-types →
- Growth hormone-producing pituitary gland neoplasm 0 trials · 5 incl. sub-types Sub-types →
- Pituitary cancer 2 trials · 4 incl. sub-types Sub-types →
- ACTH-producing pituitary gland neoplasm 1 trial Sub-types →
- Benign neoplasm of pituitary gland 0 trials
- Posterior pituitary gland neoplasm 0 trials Sub-types →
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Anterior pituitary gland disorder 1 trial · 60 incl. sub-types
2 sub-types
- Hyperpituitarism 0 trials · 59 incl. sub-types Sub-types →
- Adenohypophysitis 0 trials
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Hypopituitarism 5 trials · 46 incl. sub-types
3 sub-types
- Combined pituitary hormone deficiencies, genetic form 1 trial · 42 incl. sub-types Sub-types →
- Acquired pituitary hormone deficiency 0 trials · 1 incl. sub-types Sub-types →
- Kaplowitz-Bodurtha syndrome 0 trials
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Neurohypophyseal diabetes insipidus 9 trials
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Inappropriate ADH syndrome 5 trials
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Hypophysitis 2 trials
3 sub-types
- Granulomatous hypophysitis 0 trials
- Immunotherapy induced hypophysitis 0 trials
- Primary hypophysitis 0 trials Sub-types →
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Necrosis of pituitary 0 trials · 1 incl. sub-types
1 sub-type
- Pituitary gland infarction 0 trials · 1 incl. sub-types Sub-types →
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Empty sella syndrome 0 trials
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Pituitary hypoplasia 0 trials
Most studied deeper sub-types
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Can a glowing dye help surgeons remove pituitary tumors more completely?
Disease control CompletedThis trial tests whether giving a fluorescent dye called indocyanine green during endoscopic surgery helps surgeons remove non-functioning pituitary macroadenomas more completely. About 34 adults with these tumors will be randomly assigned to receive the dye or not during surgery…
Sponsor: Tomislav Felbabić • Aim: Disease control
Last updated Aug 15, 2026 00:00 UTC
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Weekly shot could replace daily growth hormone injections for children
Disease control CompletedThis phase 3 trial tests a long-acting growth hormone called TransCon hGH, given as a once-weekly injection, in about 150 children with growth hormone deficiency. The study aims to see if the weekly shot is safe and helps children grow at a normal rate. All participants receive t…
Phase 3 • Sponsor: Ascendis Pharma Endocrinology Division A/S • Aim: Disease control
Last updated Jul 09, 2026 00:00 UTC
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Weekly shot could replace daily needles for kids with growth hormone deficiency
Disease control CompletedThis phase 3 trial tests whether a once-weekly injection of TransCon hGH works as well as daily growth hormone injections in prepubertal children with growth hormone deficiency. About 150 children who have not received growth hormone treatment before will receive either the weekl…
Phase 3 • Sponsor: Ascendis Pharma Endocrinology Division A/S • Aim: Disease control
Last updated Jul 09, 2026 00:00 UTC
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Weekly shot could replace daily needles for kids with growth hormone deficiency
Disease control CompletedThis study tests a long-acting growth hormone called TransCon hGH, given as a once-weekly injection, in children with growth hormone deficiency who have already completed a prior TransCon trial. The goal is to see if the weekly shot remains safe and effective over the long term. …
Phase 3 • Sponsor: Ascendis Pharma A/S • Aim: Disease control
Last updated Jul 09, 2026 00:00 UTC
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Immunotherapy combo shows promise for tough pituitary tumors
Disease control CompletedThis phase 2 trial tested two immunotherapy drugs, nivolumab and ipilimumab, in 10 patients with aggressive pituitary tumors that worsened after surgery and radiation. The goal was to see if the combination could shrink tumors or slow their growth. Researchers also monitored side…
Phase 2 • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 13:01 UTC
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Targeted pill shows promise for rare genetic cancers
Disease control CompletedThis study tested an experimental drug called ENV-101 (taladegib) in 20 adults with advanced solid tumors that have a specific genetic mutation (PTCH1 loss-of-function). The drug works by blocking a growth pathway in cancer cells. Researchers measured how many patients' tumors sh…
Phase 2 • Sponsor: Endeavor Biomedicines, Inc. • Aim: Disease control
Last updated Jun 27, 2026 09:10 UTC
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New hope for kids with gigantism: daily shot may tame growth hormone
Disease control CompletedThis study tested a drug called pegvisomant in children aged 2 to 18 with gigantism, a condition where the body makes too much growth hormone. The goal was to see if the drug could safely lower hormone levels and slow down abnormal growth. Participants received daily injections a…
Phase 3 • Sponsor: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) • Aim: Disease control
Last updated Jun 27, 2026 07:56 UTC
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Can a diabetes drug reveal hidden hormone deficiencies?
Knowledge-focused CompletedThis study tested whether people with hypopituitarism (a condition where the pituitary gland doesn't work properly) have lower oxytocin levels compared to healthy individuals. Researchers gave participants a drug called exenatide (a GLP1 receptor agonist) to see if it could stimu…
Phase 4 • Sponsor: Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:13 UTC