Pituitary gland adenoma
MONDO:0006373A non-metastasizing tumor that arises from the adenohypophysial cells of the anterior lobe of the pituitary gland. The tumor can be hormonally functioning or not. The diagnosis can be based on imaging studies and/or radioimmunoassays. Due to its location in the sella turcica, expansion of the tumor mass can impinge on the optic chiasm or involve the temporal lobe, third ventricle and posterior fossa A frequently associated physical finding is bitemporal hemianopsia which may progress to further visual loss.
Also known as: adenoma of pituitary, adenoma of pituitary gland, adenoma of the pituitary, adenoma of the pituitary gland, adenoma, anterior lobe pituitary gland, benign, pituitary adenoma, pituitary gland adenoma, PTAD
1588 clinical trials for this condition and its sub-types, 34 tagged with Pituitary gland adenoma itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Pituitary gland adenoma
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Familial isolated pituitary adenoma 1 trial · 31 incl. sub-types
6 sub-types
- Cushing disease due to pituitary adenoma 23 trials
- Prolactin-producing pituitary gland adenoma 11 trials
- Growth hormone secreting pituitary adenoma 1 1 trial
- Pituitary adenoma 3, multiple types 0 trials
- Pituitary adenoma 5, multiple types 0 trials
- Pituitary adenoma, growth hormone-secreting, 2 0 trials
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Functioning pituitary gland adenoma 1 trial · 24 incl. sub-types
5 sub-types
- Cushing disease due to pituitary adenoma 23 trials
- TSH producing pituitary tumor 0 trials · 2 incl. sub-types Sub-types →
- Nelson syndrome 0 trials
- Functioning gonadotropic adenoma 0 trials
- Mixed functioning pituitary adenoma 0 trials Sub-types →
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Non-functioning pituitary adenoma 8 trials · 9 incl. sub-types
2 sub-types
- Silent pituitary adenoma 1 trial
- Null pituitary adenoma 0 trials
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1 sub-type
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Chromophobe adenoma 0 trials
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Pituitary gland acidophil adenoma 0 trials
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Pituitary gland basophil adenoma 0 trials
Most studied deeper sub-types
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Can a stronger radiation dose fix hormone overload?
Disease control Not yet recruitingResearchers are testing whether a higher dose of proton beam therapy can normalise hormone levels better than standard radiotherapy in people with functioning pituitary tumours, including acromegaly and Cushing's disease. Participants receive about six weeks of either standard-do…
Phase 3 • Sponsor: University College, London • Aim: Disease control
Last updated Sep 12, 2026 00:00 UTC
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Brain surgery safety: live signal monitoring may shield speech, movement, and sight
Knowledge-focused Not yet recruitingResearchers at Odense University Hospital are testing whether monitoring brain signals during tumor surgery can help preserve functions like movement, speech, and vision. The project includes a randomized trial comparing surgery with and without motor signal monitoring, plus obse…
Sponsor: Odense University Hospital • Aim: Knowledge-focused
Last updated Aug 29, 2026 00:00 UTC
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Can a Nose-Route surgery remove skull base tumors more safely?
Knowledge-focused Not yet recruitingThis study looks at a surgical technique called the extended endoscopic endonasal approach (EEEA), which removes skull base lesions through the nose. The goal is to see how completely the tumor can be removed and how safe the procedure is. Adults with certain skull base tumors, s…
Sponsor: Assiut University • Aim: Knowledge-focused
Last updated Aug 28, 2026 00:00 UTC
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Patient education may shorten hospital stays after pituitary surgery
Knowledge-focused Not yet recruitingThis study looks at whether giving patients clear, standardized instructions before and after pituitary surgery can improve their recovery. Researchers will compare hospital stay length, complication rates, and unplanned readmissions in 102 adults having elective surgery. The goa…
Sponsor: Uludag University • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:00 UTC
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AI assistant for brain tumor surgery: a new training tool?
Knowledge-focused Not yet recruitingThis early-phase trial tests an artificial intelligence system that watches live video from pituitary tumor surgeries performed through the nose. The AI identifies anatomy, instruments, and surgical steps, displaying its analysis on tablets for the surgical team (not the lead sur…
Early phase 1 • Sponsor: University College, London • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC