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Pick disease

MONDO:0008243

A rare neurodegenerative disorder leading to dementia. It is characterized by frontotemporal lobar degeneration with accumulation of tau proteins which form Pick bodies.

Also known as: PICK disease of brain, Pick disease, lobar atrophy of brain, Pick disease of the brain, Pick's disease, dementia with lobar atrophy and neuronal cytoplasmic inclusions, lobar atrophy of the brain

43 clinical trials for this condition and its sub-types, 35 tagged with Pick disease itself.

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Part of

↑ Cerebral cortex disorder (723) ↑ Frontotemporal dementia (178) ↑ Cerebral degeneration (61)

Including sub-types (43) Tagged with Pick disease (35)

Trials to join now! 15 Not yet recruiting 3 Not yet finished but already full! 12 Completed 12 Terminated 1

Can a synthetic cannabinoid calm agitation in frontotemporal dementia?

Symptom relief Stopped early

This phase 2 trial tests whether nabilone, a synthetic cannabinoid, can reduce agitation in people with frontotemporal dementia (FTD). Participants receive both nabilone and a placebo in random order to compare effects. The study includes adults with behavioral variant FTD or pri…

Phase 2 • Sponsor: Simon Ducharme, MD • Aim: Symptom relief

Last updated Jul 30, 2026 00:00 UTC

Pick disease

Where it sits in the disease tree

Can a synthetic cannabinoid calm agitation in frontotemporal dementia?