Peyronie disease
MONDO:0008231A condition characterized by hardening of the penis due to the formation of fibrous plaques on the dorsolateral aspect of the penis, usually involving the membrane (tunica albuginea) surrounding the erectile tissue (corpus cavernosum penis). This may eventually cause a painful deformity of the shaft or constriction of the urethra, or both.
Also known as: Peyronie disease, Peyronie's disease, Peyronie's fibromatosis, penile fibromatosis, penile induration, penis fibromatosis
1438 clinical trials for this condition and its sub-types, 12 tagged with Peyronie disease itself.
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Can a new injection strategy help men with Peyronie's disease who failed standard treatment?
Disease control CompletedThis trial is testing whether a new way of giving collagenase injections can help men with Peyronie's disease who have not improved with standard treatment. Peyronie's disease causes a curved, painful erection due to scar tissue. The study will compare men who receive up to 8 inj…
Phase 4 • Sponsor: Charitable Union for the Research and Education of Peyronie's Disease • Aim: Disease control
Last updated Aug 28, 2026 00:00 UTC
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Can your own blood straighten the curve? PRP takes on Peyronie's
Disease control CompletedThis trial tests whether injecting platelet-rich plasma (PRP) — a concentrate made from a person's own blood — into the penile plaque can reduce curvature and ease symptoms in men with Peyronie's disease. Half the participants receive PRP injections and half receive a placebo (sa…
Phase 2 • Sponsor: University of Miami • Aim: Disease control
Last updated Aug 05, 2026 00:00 UTC
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New penile implant study shows promise for Men's confidence
Disease control CompletedThis study tested a silicone block placed under the skin of the penis to improve its size, shape, and appearance. It included 40 men who were unhappy with their penile girth or length. The main goal was to check safety and measure changes in size and patient satisfaction.
Sponsor: International Medical Devices, Inc. • Aim: Disease control
Last updated Jun 27, 2026 12:01 UTC