Persistent truncus arteriosus
MONDO:0018072A rare congenital cardiovascular disorder characterized by the failure of the embryologic structure truncus arteriosus to divide into the aorta and pulmonary trunk. It results in the presence of a single vessel instead of two vessels leading out of the heart. Clinical signs and symptoms include cyanosis that is present at birth, poor growth, dyspnea, tachypnea, arrhythmia, cardiomegaly, and heart failure. If it is not surgically repaired, it leads to death.
Also known as: TAC, Truncus Arteriosus, common aorticopulmonary trunk, common arterial trunk, common truncus arteriosus, persistent truncus arteriosus, persistent truncus arteriosus (disease), truncus arteriosus
84 clinical trials for this condition and its sub-types, 8 tagged with Persistent truncus arteriosus itself.
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Browse by category →Sub-types of Persistent truncus arteriosus
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App-Based exercise program aims to strengthen hearts in congenital disease
Disease control Stopped earlyThis study tests a remote, app-enabled exercise program designed for people aged 10 to 50 with congenital heart disease. Participants use a smartphone app with exercise modules and wearable devices to track heart rate and progress. The goal is to see if this approach can safely i…
Sponsor: Duke University • Aim: Disease control
Last updated Aug 07, 2026 00:00 UTC
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Can a brain zap and computer game sharpen aging minds?
Symptom relief Stopped earlyThis study tested whether combining a computer-based speed-of-processing training with a gentle electrical brain stimulation (alpha-tACS) could improve how quickly people with mild cognitive impairment process visual information. The trial planned to enroll 40 adults aged 65 and …
Sponsor: Portucalense University • Aim: Symptom relief
Last updated Jun 26, 2026 16:29 UTC