Persistent hyperplastic primary vitreous

MONDO:0019631

A developmental ocular anomaly in which the primary vitreous body and its surrounding hyaloid vasculature failed to regress. It is usually unilateral and characterized by cataract; microphthalmos (small eyeballs), and retrolenticular fibrovascular tissue. (from Yanoff: Ophthalmology, 2nd ed.)

Also known as: PFVS, PHPV, congenital retinal detachment, ncRNA disease, non-syndromic congenital retinal non-attachment, persistent fetal vasculature syndrome, persistent foetal vasculature syndrome

13 clinical trials for this condition and its sub-types, 0 tagged with Persistent hyperplastic primary vitreous itself.

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Where it sits in the disease tree

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Part of

↑ Vitreous disorder (50) ↑ Congenital vitreoretinal dysplasia (9)

Sub-types of Persistent hyperplastic primary vitreous

Including sub-types (13) Tagged with Persistent hyperplastic primary vitreous (0)

Trials to join now! 5 Not yet recruiting 1 Completed 6 Terminated 1

VR headsets tested as a possible treatment for blindness

Disease control Stopped early

This study tested whether using a virtual reality headset for one-hour sessions could help regenerate damaged optic nerves and improve vision in people with glaucoma or other retinal diseases. The idea came from promising results in rodents. However, the trial was terminated earl…

Sponsor: Stanford University • Aim: Disease control

Last updated Jun 27, 2026 08:03 UTC

Persistent hyperplastic primary vitreous

Where it sits in the disease tree

VR headsets tested as a possible treatment for blindness