Peripheral primitive neuroectodermal tumor
MONDO:0018271A small round cell tumor with neural differentiation arising from the soft tissues or bone.
Also known as: PPNET, pPNET, peripheral PNET, peripheral neuroectodermal neoplasm, peripheral neuroectodermal tumor, peripheral neuroectodermal tumour, peripheral neuroepithelioma, peripheral primitive neuroectodermal neoplasm
2739 clinical trials for this condition and its sub-types, 7 tagged with Peripheral primitive neuroectodermal tumor itself.
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Sub-types of Peripheral primitive neuroectodermal tumor
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Askin tumor 0 trials
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New hope for kids with rare cancers: targeted drug selpercatinib tested in phase 2 trial
Disease control OngoingThis phase 2 trial tests the drug selpercatinib in children and young adults (ages 1 to 21) with advanced cancers that have a specific genetic change called a RET alteration. The goal is to see if the drug can shrink tumors or stop them from growing. Only one participant has been…
Phase 2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Aug 05, 2026 00:00 UTC
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New hope for rare bone cancer: targeted drug added to chemo in major trial
Disease control OngoingThis study tests whether adding a targeted drug called ganitumab to standard chemotherapy helps people with newly diagnosed Ewing sarcoma that has spread. The trial includes 312 participants and aims to see if the combination improves survival without the cancer growing back. The…
Phase 3 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jul 31, 2026 00:00 UTC
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Can DNA tests pick the right cancer drug for kids?
Knowledge-focused OngoingThis study screens children and teens with advanced solid tumors, lymphomas, or histiocytic disorders to find genetic changes in their cancer cells. Participants undergo biopsies and scans to identify mutations that can be targeted by specific drugs. The goal is to see if matchin…
Phase 2 • Sponsor: National Cancer Institute (NCI) • Aim: Knowledge-focused
Last updated Jul 26, 2026 00:00 UTC
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Blood test could revolutionize sarcoma monitoring
Knowledge-focused OngoingThis study is testing whether a liquid biopsy (a blood test that detects tumor DNA) can help predict outcomes for people with Ewing sarcoma or osteosarcoma. Researchers will collect blood samples from 340 patients at diagnosis and track their health over time. The goal is to see …
Sponsor: Dana-Farber Cancer Institute • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC