Peripheral neuropathy
MONDO:0005244A disorder affecting the peripheral nervous system. It manifests with pain, tingling, numbness, and muscle weakness. It may be the result of physical injury, toxic substances, viral diseases, diabetes, renal failure, cancer, and drugs.
Also known as: neuropathy, peripheral nerve disorder, peripheral neuropathy
1469 clinical trials for this condition and its sub-types, 93 tagged with Peripheral neuropathy itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Peripheral neuropathy
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Hereditary peripheral neuropathy 6 trials · 478 incl. sub-types
65 sub-types
- Carpal tunnel syndrome 165 trials Sub-types →
- Charcot-Marie-Tooth disease 51 trials · 77 incl. sub-types Sub-types →
- Familial amyloid neuropathy 52 trials · 54 incl. sub-types Sub-types →
- Hereditary sensory and autonomic neuropathy 52 trials · 54 incl. sub-types Sub-types →
- Proximal spinal muscular atrophy 14 trials · 42 incl. sub-types Sub-types →
- Metachromatic leukodystrophy 20 trials Sub-types →
- Krabbe disease 15 trials Sub-types →
- Sandhoff disease 13 trials Sub-types →
- Tay-Sachs disease 13 trials Sub-types →
- Chediak-Higashi syndrome 9 trials
- Leigh syndrome 9 trials Sub-types →
- Peroxisome biogenesis disorder 4 trials · 8 incl. sub-types Sub-types →
- Adrenomyeloneuropathy 7 trials
- Cerebrotendinous xanthomatosis 6 trials
- Kearns-Sayre syndrome 5 trials
- Distal hereditary motor neuropathy 0 trials · 4 incl. sub-types Sub-types →
- Hereditary neuropathy with liability to pressure palsies 4 trials
- Mitochondrial neurogastrointestinal encephalomyopathy 4 trials Sub-types →
- Ornithine aminotransferase deficiency 4 trials
- Pyruvate dehydrogenase deficiency 2 trials · 4 incl. sub-types Sub-types →
- NARP syndrome 3 trials
- Biotinidase deficiency 3 trials
- Coenzyme Q10 deficiency 3 trials Sub-types →
- Giant axonal neuropathy 2 trials · 3 incl. sub-types Sub-types →
- Hereditary motor and sensory neuropathy 3 trials Sub-types →
- Methylmalonic aciduria and homocystinuria type cblC 3 trials
- Mitochondrial DNA depletion syndrome 4a 3 trials
- Abetalipoproteinemia 2 trials
- Fumaric aciduria 2 trials
- Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy 2 2 trials
- Niemann-Pick disease type B 1 trial
- PRPS1 deficiency disorder 1 trial
- Adult polyglucosan body disease 1 trial
- Familial isolated deficiency of vitamin E 1 trial
- Homocystinuria due to methylene tetrahydrofolate reductase deficiency 1 trial
- Long chain 3-hydroxyacyl-CoA dehydrogenase deficiency 1 trial
- Neuropathy, congenital hypomelinating 0 trials · 1 incl. sub-types Sub-types →
- Sensory ataxic neuropathy, dysarthria, and ophthalmoparesis 1 trial Sub-types →
- Charcot-Marie-Tooth disease type 5 0 trials
- EMILIN-1-related connective tissue disease 0 trials
- Finnish type amyloidosis 0 trials
- PHARC syndrome 0 trials
- VPS13A-related neurodegenerative disease 0 trials
- Amyotrophic neuralgia 0 trials
- Ataxia - oculomotor apraxia type 4 0 trials
- Attenuated Chédiak-Higashi syndrome 0 trials
- Beta-mannosidosis 0 trials
- Cataract-growth hormone deficiency-sensory neuropathy-sensorineural hearing loss-skeletal dysplasia syndrome 0 trials
- Congenital trigeminal anesthesia 0 trials
- Familial episodic pain syndrome 0 trials Sub-types →
- Familial recurrent peripheral facial palsy 0 trials
- Hereditary motor and sensory neuropathy, Okinawa type 0 trials Sub-types →
- Hereditary sensory and autonomic neuropathy with spastic paraplegia 0 trials
- Infantile axonal neuropathy 0 trials
- Meralgia paraesthetica, familial 0 trials
- Neurodegeneration with brain iron accumulation 2A 0 trials
- Neuropathy with hearing impairment 0 trials
- Neuropathy, hereditary sensory and autonomic, type IId 0 trials
- Non-progressive predominantly posterior cavitating leukoencephalopathy with peripheral neuropathy 0 trials
- Optic atrophy-ataxia-peripheral neuropathy-global developmental delay syndrome 0 trials
- Oxoglutaricaciduria 0 trials
- Peripheral motor neuropathy, childhood-onset, biotin-responsive 0 trials
- Primary CD59 deficiency 0 trials
- Progressive demyelinating neuropathy with bilateral striatal necrosis 0 trials
- Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy 1 0 trials
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Neuralgia 238 trials · 383 incl. sub-types
5 sub-types
- Sciatica 46 trials · 68 incl. sub-types Sub-types →
- Cranial neuralgia 0 trials · 53 incl. sub-types Sub-types →
- Post-infectious neuralgia 0 trials · 33 incl. sub-types Sub-types →
- Pudendal neuralgia 9 trials
- Familial episodic pain syndrome 0 trials Sub-types →
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Nerve compression syndrome 24 trials · 207 incl. sub-types
3 sub-types
- Carpal tunnel syndrome 165 trials Sub-types →
- Piriformis syndrome 25 trials
- Meralgia paresthetica 5 trials Sub-types →
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Diabetic neuropathy 181 trials · 192 incl. sub-types
2 sub-types
- Diabetic polyneuropathy 50 trials
- Diabetic autonomic neuropathy 7 trials
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Chemotherapy-induced neuropathy 171 trials
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Polyneuropathy 32 trials · 132 incl. sub-types
10 sub-types
- Polyradiculoneuropathy 1 trial · 64 incl. sub-types Sub-types →
- Chronic polyneuropathy 0 trials · 62 incl. sub-types Sub-types →
- Demyelinating polyneuropathy 2 trials · 62 incl. sub-types Sub-types →
- Critical illness polyneuropathy 39 trials
- Polyneuritis 3 trials
- Toxic polyneuropathy 1 trial · 3 incl. sub-types Sub-types →
- Idiopathic progressive polyneuropathy 0 trials
- Organophosphate-induced delayed polyneuropathy 0 trials
- Paraneoplastic polyneuropathy 0 trials
- Polyneuropathy in collagen vascular disease 0 trials
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Mononeuropathy 4 trials · 111 incl. sub-types
7 sub-types
- Sciatic neuropathy 9 trials · 72 incl. sub-types Sub-types →
- Ulnar neuropathy 7 trials · 21 incl. sub-types Sub-types →
- Peroneal neuropathy 9 trials
- Femoral neuropathy 7 trials
- Radial neuropathy 1 trial Sub-types →
- Tibial neuropathy 0 trials · 1 incl. sub-types Sub-types →
- Mononeuritis simplex 0 trials Sub-types →
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Acquired peripheral neuropathy 0 trials · 95 incl. sub-types
12 sub-types
- Cranial neuralgia 0 trials · 53 incl. sub-types Sub-types →
- Multifocal motor neuropathy 9 trials
- Pudendal neuralgia 9 trials
- POEMS syndrome 8 trials
- Polyneuropathy associated with IgM monoclonal gammapathy with anti-MAG 8 trials
- Non-recovering obstetric brachial plexus lesion 6 trials
- Anterior cutaneous nerve entrapment syndrome 2 trials
- Radiation-induced plexopathy 1 trial
- CANOMAD syndrome 0 trials
- Axonal polyneuropathy associated with IgG/IgM/IgA monoclonal gammopathy 0 trials
- Neuralgic amyotrophy 0 trials
- Simple cryoglobulinemia 0 trials
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Nerve plexus disorder 0 trials · 75 incl. sub-types
4 sub-types
- Brachial plexus neuropathy 13 trials · 72 incl. sub-types Sub-types →
- Lumbosacral plexus lesion 0 trials · 2 incl. sub-types Sub-types →
- Radiation-induced plexopathy 1 trial
- Nerve plexus neoplasm 0 trials Sub-types →
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Sensory peripheral neuropathy 4 trials · 58 incl. sub-types
1 sub-type
- Hereditary sensory and autonomic neuropathy 52 trials · 54 incl. sub-types Sub-types →
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Traumatic neuropathy 55 trials
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Neuritis 18 trials · 29 incl. sub-types
7 sub-types
- Vestibular neuronitis 9 trials
- Polyneuritis 3 trials
- Brachial plexus neuritis 0 trials Sub-types →
- Mononeuritis simplex 0 trials Sub-types →
- Motor nerve neuritis 0 trials Sub-types →
- Neuritis of upper limb 0 trials Sub-types →
- Neuroretinitis 0 trials
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Peripheral nerve lesion 1 trial · 12 incl. sub-types
4 sub-types
- Femoral neuropathy 7 trials
- Lesion of sciatic nerve 2 trials Sub-types →
- Ulnar nerve lesion 2 trials
- Radial nerve lesion 0 trials
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Autonomic neuropathy 7 trials · 10 incl. sub-types
2 sub-types
- Diabetic autonomic neuropathy 7 trials
- Horner syndrome 0 trials Sub-types →
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Chronic idiopathic neuropathy 5 trials
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Neuropathy, small fiber 4 trials
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Axonal neuropathy 1 trial · 4 incl. sub-types
3 sub-types
- Giant axonal neuropathy 2 trials · 3 incl. sub-types Sub-types →
- Congenital axonal neuropathy with encephalopathy 0 trials
- Infantile axonal neuropathy 0 trials
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Infectious neuropathy 2 trials
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Vasculitic neuropathy 2 trials
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Autoimmune neuropathy 1 trial
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Ischemic neuropathy 1 trial
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Sarcoid neuropathy 1 trial
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Motor peripheral neuropathy 0 trials · 1 incl. sub-types
9 sub-types
- Charcot-Marie-Tooth disease axonal type 2C 1 trial
- Charcot-Marie-Tooth disease type 4G 0 trials
- Charcot-Marie-Tooth disease type 5 0 trials
- Glossopharyngeal motor neuropathy 0 trials
- Hereditary motor and sensory neuropathy, Okinawa type 0 trials Sub-types →
- Motor nerve neuritis 0 trials Sub-types →
- Neuropathy, hereditary motor and sensory, type 6A 0 trials
- Neuropathy, hereditary motor and sensory, type 6B 0 trials
- Peripheral motor neuropathy, childhood-onset, biotin-responsive 0 trials
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Radiation-induced neuropathy 0 trials · 1 incl. sub-types
1 sub-type
- Radiation-induced plexopathy 1 trial
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Idiopathic small fibers neuropathy 0 trials
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Neuropathy in cryoglobulinemia 0 trials
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Neuropathy in endocrine disorder 0 trials
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Uremic neuropathy 0 trials
Most studied deeper sub-types
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Robots map how brain and nerve injuries disrupt everyday arm tasks
Knowledge-focused Stopped earlyResearchers at the University of Pennsylvania are studying how people with stroke, upper limb amputation, spinal cord injury, or cerebral palsy move their arms during common daily activities like drinking and pouring. The study uses two passive desktop robots to track the motion …
Sponsor: University of Pennsylvania • Aim: Knowledge-focused
Last updated Sep 12, 2026 00:00 UTC
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Could a simple blood test track nerve damage? a study investigates NT-3 levels in neuropathy.
Knowledge-focused Stopped earlyThis study measures levels of a protein called NT-3 in the blood of people with peripheral neuropathy or Charcot-Marie-Tooth disease. Researchers will compare these levels with measures of muscle strength, mobility, and daily function. The goal is to see whether NT-3 levels corre…
Sponsor: Zarife Sahenk • Aim: Knowledge-focused
Last updated Jul 31, 2026 00:00 UTC
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Laughing gas linked to nerve damage in young users
Knowledge-focused Stopped earlyThis study looked back at 20 young people who came to the hospital with nerve problems after using nitrous oxide (laughing gas) for fun. Researchers measured muscle strength, balance, and disability to understand how the gas harms the nervous system. The goal was to learn more ab…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC