Periodic fever syndrome
MONDO:0015137Fevers of unknown etiology recurring over months or years.
34 clinical trials for this condition and its sub-types, 2 tagged with Periodic fever syndrome itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Periodic fever syndrome
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Hereditary periodic fever syndrome 5 trials · 24 incl. sub-types
6 sub-types
- Familial Mediterranean fever 15 trials Sub-types →
- Cryopyrin-associated periodic syndrome 10 trials Sub-types →
- TNF receptor 1-associated periodic fever syndrome 4 trials
- Mevalonate kinase deficiency 3 trials · 4 incl. sub-types Sub-types →
- Periodic fever-infantile enterocolitis-autoinflammatory syndrome 2 trials
- Autoinflammation, panniculitis, and dermatosis syndrome, autosomal recessive 0 trials
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Periodic fever syndrome of childhood 0 trials
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Unexplained periodic fever syndrome 0 trials
Most studied deeper sub-types
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New drug aims to tame rare immune storms
Disease control OngoingThis phase 2 study tests a drug called MAS825 in 17 people with rare genetic conditions that cause severe inflammation. The goal is to see if the drug can prevent disease flares better than a placebo. Participants will be monitored for safety and effectiveness over several period…
Phase 2 • Sponsor: Novartis Pharmaceuticals • Aim: Disease control
Last updated Aug 02, 2026 00:00 UTC
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New hope for rare fever disorder: drug targets stubborn cases
Disease control CancelledThis study tests whether anakinra (Kineret), a daily injection, can reduce monthly attacks in Chinese patients with Familial Mediterranean Fever (FMF) who do not respond to standard colchicine treatment. Three patients aged 2 years and older will receive anakinra for 6 months, wi…
Phase 4 • Sponsor: Swedish Orphan Biovitrum • Aim: Disease control
Last updated Jul 01, 2026 00:00 UTC
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Can a smartphone app unlock the link between infections and FMF attacks?
Knowledge-focused By invitation onlyThis study will enroll 40 children aged 8-18 with Familial Mediterranean Fever (FMF) to see if infections trigger disease flares. Participants will use a mobile app to log symptoms like fever, cough, or sore throat in real time. The goal is to better understand the infection-flar…
Sponsor: Istanbul University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC