Perianal Crohn disease
MONDO:0005537A Crohn disease involving a pathogenic inflammatory response in the anal region.
Also known as: perianal Crohn's disease
63 clinical trials for this condition and its sub-types, 10 tagged with Perianal Crohn disease itself.
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New drug shows promise for healing Crohn's fistulas
Disease control OngoingThis study tests a drug called guselkumab in people with Crohn's disease who have abnormal tunnels (fistulas) near the anus. The goal is to see if the drug can close these fistulas and prevent new ones, using MRI scans to confirm healing. About 288 adults who have not responded t…
Phase 3 • Sponsor: Janssen-Cilag Ltd. • Aim: Disease control
Last updated Aug 30, 2026 00:00 UTC
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Can stem cells harvested during surgery heal Crohn's fistulas?
Disease control CancelledThis trial explores whether stem cells taken from a patient's own bone marrow during surgery can help treat fistulas—abnormal tunnels under the skin—caused by Crohn's disease. The stem cells are prepared quickly in the operating room and injected into the fistula tract. Researche…
Sponsor: Oxford University Hospitals NHS Trust • Aim: Disease control
Last updated Jul 29, 2026 00:00 UTC