Periampullary adenocarcinoma

This study tests whether using a real-time continuous glucose monitor (RT-CGM) during pancreaticoduodenectomy (a complex surgery) helps keep patients' blood sugar in a safe range and improves recovery. About 246 adults scheduled for this surgery will be randomly assigned to stand…

This study tested a new way to reconnect the pancreas to the intestine during Whipple surgery for certain cancers. The new method uses a stent and wraps the connection with omentum (fatty tissue) to try to prevent leaks. 48 patients were split into two groups to compare the new t…

This study compared two surgical methods—laparoscopic (keyhole) and open surgery—for treating a rare cancer near the pancreas called periampullary adenocarcinoma. Forty patients were enrolled to see which approach led to fewer complications like pancreatic fistula. The goal was t…

This completed Phase 4 trial tested a new surgical technique during Whipple surgery for resectable periampullary tumors. The method uses an omental patch and surgical glue to reinforce the pancreatic connection, aiming to reduce leaks, bleeding, and stomach emptying problems. Thi…

This study tested whether a device that gently stimulates the vagus nerve through the ear could reduce delayed stomach emptying after a major pancreatic surgery (pancreaticoduodenectomy). 84 patients were randomly assigned to receive the stimulation during surgery or not. The goa…

This study is testing whether a special type of ultrasound, called endoscopic ultrasound elastography, can predict the texture of the pancreas and the risk of a pancreatic fistula after a major surgery called pancreaticoduodenectomy. The study will enroll 100 adults scheduled for…

This study looked at how patients recover after robotic surgery to remove part of the pancreas (pancreaticoduodenectomy). It included 91 adults with tumors in the pancreas or nearby areas. The main goal was to see how long they stayed in the hospital and how quickly they returned…

This completed study followed 44 adults who had Whipple surgery for cancers near the pancreas. Researchers measured changes in the remaining pancreas, including its size, metabolism, and nutrition levels, before surgery and at 3 and 6 months after. The goal was to learn how the b…