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Keyhole vs. open surgery: which is safer for pancreatic cancer?

NCT ID NCT07388082

Disease control Sponsor: Theodor Bilharz Research Institute Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compared two surgical methods—laparoscopic (keyhole) and open surgery—for treating a rare cancer near the pancreas called periampullary adenocarcinoma. Forty patients were enrolled to see which approach led to fewer complications like pancreatic fistula. The goal was to help doctors decide if the less invasive keyhole method is a safe routine option.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

40 people

The number who actually took part.

Started

Aug 2023

Finished

Oct 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 80 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * • Body mass index \<28.0 kg/m2. * Ampullary tumors, duodenal tumors restricted to the second part of the duodenum, or lower common bile duct tumors. * Carefully confirmed resectability of the tumors based on preoperative radiology conducted by experienced radiologists and surgeons. Exclusion Criteria: * • Patients with \>180 degrees superior mesenteric artery encasement * Any celiac abutment. * Unreconstructable superior mesenteric vein/portal occlusion" Aortic invasion or encasement. * A history of previous upper abdominal surgery. * Tumors extending to the uncinate. * Severe cardiorespiratory comorbidities.

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Conditions

The condition(s) this trial relates to.

periampullary adenocarcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Periampullary carcinoma

Contacts and locations

Locations

  • Theodor Bilharz Research Institute

    Giza, Egypt

More trials for these conditions

Other studies related to the condition(s) this trial covers.