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Pemphigus
MONDO:0006594Pemphigus is a group of rare autoimmune diseases that cause blistering of the skin and mucous membranes (mouth, nose, throat, eyes, and genitals).This conditioncan occur at any age, but often strikes people in middle or older age. Studies have shown that some populations may be at greater risk for certain types of pemphigus. For instance, people of Jewish descent and those from India, Southeast Europe, and the Middle East are at greater risk for pemphigus vulargis, while pemphigus foliaceus is more common in North America, Turkey, and South America. Pemphigus is a chronic disease which is best controlled by early diagnosis and treatment.Treatment includes steroids to reduce inflammation,drugs that suppress the immune system responseand antibiotics to treat associated infections. There are four main types of pemphigus: Pemphigus vulgaris Pemphigus foliaceus IgA pemphigus Paraneoplastic pemphigus
64 clinical trials for this condition and its sub-types, 20 tagged with Pemphigus itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Pemphigus
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Pemphigus vulgaris 13 trials
1 sub-type
- Pemphigus vegetans 0 trials
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Pemphigus foliaceus 3 trials · 6 incl. sub-types
1 sub-type
- Pemphigus and fogo selvagem 3 trials
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Hailey-Hailey disease 4 trials
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Herpetiform pemphigus 0 trials
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Pemphigoid gestationis 0 trials
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Pemphigus erythematosus 0 trials
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Rituximab shows promise for long-term control of rare blistering skin disease
Disease control CompletedThis study followed 80 patients with pemphigus, a rare autoimmune disease that causes painful blisters on skin and mucous membranes. Researchers wanted to see how safe and effective rituximab (a drug that targets certain immune cells) is over the long term, compared to standard h…
Phase 3 • Sponsor: University Hospital, Rouen • Aim: Disease control
Last updated Jun 27, 2026 12:35 UTC
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Dose debate: which rituximab regimen works best for rare blistering disease?
Disease control CompletedThis study looked back at 275 pemphigus patients to see how different doses of rituximab affected disease control and relapse. Pemphigus is a rare autoimmune disease that causes painful blisters on skin and mucous membranes. Researchers tracked outcomes like flare-ups, side effec…
Sponsor: Ruijin Hospital • Aim: Disease control
Last updated Jun 27, 2026 11:00 UTC
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Insulin ointment shows promise for speeding up wound healing in rare blistering disease
Symptom relief CompletedThis study tested whether applying insulin directly to skin sores helps them heal faster in people with pemphigus vulgaris, a rare autoimmune blistering disease. Twenty patients each had three similar sores treated with either long-acting insulin, short-acting insulin, or a saltw…
Phase 2 • Sponsor: Alexandria University • Aim: Symptom relief
Last updated Jun 27, 2026 11:00 UTC
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AI boosts doctor accuracy for rare skin diseases in new study
Knowledge-focused CompletedThis study tested whether an artificial intelligence (AI) tool could help doctors diagnose rare and tricky skin conditions like generalized pustular psoriasis (GPP). Fifteen doctors, including both general practitioners and dermatologists, looked at 100 skin images. They first ga…
Sponsor: AI Labs Group S.L • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:07 UTC
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Pemphigus study digs into hidden emotional struggles
Knowledge-focused CompletedThis study looked at 48 adults with pemphigus, a rare blistering skin disease, to understand what makes them feel vulnerable during their illness. Researchers used interviews and questionnaires to explore factors like misdiagnosis, differences in how patients and doctors see dise…
Sponsor: University Hospital, Rouen • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:02 UTC