Paraparetic variant of Guillain-Barre syndrome

MONDO:0016497

Paraparetic variant of Guillain-Barré syndrome is a rare variant of Guillain-Barré syndrome characterized by isolated leg weakness, areflexia and radicular leg pain that may simulate a cauda equina or spinal cord syndrome. The arms, ocular, facial, and oropharyngeal muscles are spared, and sphincteric function is normal.

Also known as: paraparetic variant of GBS, paraparetic variant of Guillain-Barré syndrome

38 clinical trials for this condition and its sub-types, 0 tagged with Paraparetic variant of Guillain-Barre syndrome itself.

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Where it sits in the disease tree

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↑ Guillain-Barre syndrome (39)

Including sub-types (38) Tagged with Paraparetic variant of Guillain-Barre syndrome (0)

Trials to join now! 15 Not yet recruiting 9 Not yet finished but already full! 5 Completed 8 Terminated 1

Biopsy tolerance study ends early – what we know

Knowledge-focused Stopped early

This study aimed to understand how well patients tolerate biopsies for autoimmune diseases and whether they feel properly informed. It planned to enroll 505 people but was terminated early. The results may help improve patient experience with these common procedures.

Sponsor: University Hospital, Brest • Aim: Knowledge-focused

Last updated Jun 28, 2026 00:00 UTC

Paraparetic variant of Guillain-Barre syndrome

Where it sits in the disease tree

Biopsy tolerance study ends early – what we know