Palmar fibromatosis
MONDO:0006345A superficial fibromatosis arising from the soft tissue of the palm. It is characterized by the presence of spindle-shaped fibroblasts, and an infiltrative growth pattern. It predominantly affects adult males.
Also known as: Dupuytren contracture, Dupuytren contracture (disease), palmar fibromatosis, palmar part of manus fibromatosis, Dupuytren's contracture
1452 clinical trials for this condition and its sub-types, 20 tagged with Palmar fibromatosis itself.
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Shock waves could soften hand contractures without surgery
Disease control CompletedThis study tests whether extracorporeal shock wave therapy can reduce the thickness of fibrous tissue in the hand caused by palmar fibromatosis (Dupuytren's contracture). Adults aged 18 to 70 with nodules, cords, or contractures will receive either shock wave therapy plus standar…
Sponsor: Cairo University • Aim: Disease control
Last updated Jul 16, 2026 00:00 UTC
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New device may straighten bent fingers without surgery
Disease control CompletedThis study tested a device called MiniFlo that slowly stretches bent fingers back into place in people with advanced Dupuytren's disease. 18 adults with stage III-IV disease used the device. Researchers measured how much finger straightening improved and checked for pain or side …
Sponsor: Azienda Ospedaliera Universitaria Integrata Verona • Aim: Disease control
Last updated Jun 27, 2026 12:03 UTC
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New anesthesia mix may ease pain after hand surgery
Symptom relief CompletedThis study tested two local anesthesia methods for hand, wrist, or elbow surgery. One used lidocaine alone, the other added ropivacaine for longer pain relief. 91 adults participated. Researchers measured pain and recovery quality 48 hours after surgery to see if the combination …
Phase 1 • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Symptom relief
Last updated Jun 27, 2026 08:03 UTC
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Missing hand muscle may shield against dupuytren disease
Knowledge-focused CompletedThis study compared 243 people with and without Dupuytren disease to see if having the palmaris longus tendon (a small hand tendon not everyone has) is linked to the condition. Researchers used simple hand tests and ultrasound to check for the tendon. The goal is to understand if…
Sponsor: Universitaire Ziekenhuizen KU Leuven • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:00 UTC