Osteogenesis imperfecta type 4
MONDO:0008148Osteogenesis imperfecta type IV is a moderate type of osteogenesis imperfecta (OI), a genetic disorder characterized by increased bone fragility, low bone mass and susceptibility to bone fractures. Patients with type IV have moderately short stature, mild to moderate scoliosis, grayish or white sclera, and dentinogenesis imperfecta (DI).
Also known as: OI type 4, OI4, osteogenesis imperfecta type IV, OI type IV, OI, type 4, common variable OI with normal sclerae, osteogenesis imperfecta with normal sclerae, osteogenesis imperfecta, type 4
7 clinical trials for this condition and its sub-types, 7 tagged with Osteogenesis imperfecta type 4 itself.
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New shot aims to fortify fragile bones in brittle bone disease trial
Disease control Recruiting nowThis study tests a drug called AGA2115 in 80 adults with osteogenesis imperfecta (brittle bone disease) types I, III, or IV. Participants receive either the drug or a placebo as a shot under the skin. The main goal is to see if the drug increases bone density in the spine after 1…
Phase 2 • Sponsor: Angitia Incorporated Limited • Aim: Disease control
Last updated Aug 19, 2026 00:00 UTC
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New shot aims to toughen fragile bones in rare disease
Disease control Recruiting nowThis phase 2 trial tests a drug called AGA2115 in 48 Chinese adults and adolescents with osteogenesis imperfecta (types I, III, IV), a condition that makes bones brittle. Participants receive one of three dose schedules by injection under the skin. The study checks for side effec…
Phase 2 • Sponsor: Angitia Biopharmaceuticals Guangzhou Limited • Aim: Disease control
Last updated Jun 27, 2026 14:01 UTC