Osteochondrodysplasia
MONDO:0005516A term referring to disorders characterized by abnormalities in the development of bones and cartilage.
Also known as: skeletal dysplasia, congenital skeletal dysplasia, osteochondrodysplasia, cartilage development disorder, congenital anomaly of cartilage
381 clinical trials for this condition and its sub-types, 12 tagged with Osteochondrodysplasia itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Osteochondrodysplasia
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Osteogenesis imperfecta 35 trials · 330 incl. sub-types
10 sub-types
- Osteogenesis imperfecta and a reduction of bone mineral density. 0 trials · 308 incl. sub-types Sub-types →
- Brittle bone disorder 4 trials Sub-types →
- COL1A2-related osteogenesis imperfecta 0 trials
- High bone mass osteogenesis imperfecta 0 trials
- Osteogenesis imperfecta type 13 0 trials
- Osteogenesis imperfecta, IIA 22 0 trials
- Osteogenesis imperfecta, type 20 0 trials
- Osteogenesis imperfecta, type 21 0 trials
- Osteogenesis imperfecta, type 23 0 trials
- Osteogenesis imperfecta-retinopathy-seizures-intellectual disability syndrome 0 trials
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Achondroplasia 26 trials
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Hypochondroplasia 9 trials
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Spondyloepiphyseal dysplasia 0 trials · 8 incl. sub-types
44 sub-types
- Stickler syndrome 2 trials · 4 incl. sub-types Sub-types →
- COL2A1-related spondyloepiphyseal dysplasia 0 trials · 3 incl. sub-types Sub-types →
- Roifman syndrome 1 trial
- Progressive pseudorheumatoid arthropathy of childhood 1 trial
- Spondyloepiphyseal dysplasia tarda 0 trials · 1 incl. sub-types Sub-types →
- Spondyloepiphyseal dysplasia, Cantu type 1 trial
- CODAS syndrome 0 trials
- Dyggve-Melchior-Clausen disease 0 trials Sub-types →
- Ehlers-Danlos syndrome, spondylocheirodysplastic type 0 trials
- MGP-related spondyloepiphyseal dysplasia 0 trials
- MIR140-related spondyloepiphyseal dysplasia 0 trials
- Marshall syndrome 0 trials
- Richieri Costa-da Silva syndrome 0 trials
- Schimke immuno-osseous dysplasia 0 trials
- Schwartz-Jampel syndrome 0 trials Sub-types →
- Silverman-Handmaker type dyssegmental dysplasia 0 trials
- Smith-McCort dysplasia 0 trials Sub-types →
- Steel syndrome 0 trials
- TMEM165-congenital disorder of glycosylation 0 trials
- Wolcott-Rallison syndrome 0 trials
- X-linked intellectual disability-cerebellar hypoplasia-spondylo-epiphyseal dysplasia syndrome 0 trials
- X-linked spondyloepimetaphyseal dysplasia 0 trials
- Anauxetic dysplasia 0 trials Sub-types →
- Brachydactylous dwarfism, Mseleni type 0 trials
- Brachyolmia-amelogenesis imperfecta syndrome 0 trials
- Cataract-growth hormone deficiency-sensory neuropathy-sensorineural hearing loss-skeletal dysplasia syndrome 0 trials
- Cono-spondylar dysplasia 0 trials
- Dyssegmental dysplasia, Rolland-Desbuquois type 0 trials
- Even-plus syndrome 0 trials
- Hip dysplasia, Beukes type 0 trials
- Immunoskeletal dysplasia with neurodevelopmental abnormalities 0 trials
- Metatropic dysplasia 0 trials
- Otospondylomegaepiphyseal dysplasia 0 trials Sub-types →
- Progressive spondyloepimetaphyseal dysplasia-short stature-short fourth metatarsals-intellectual disability syndrome 0 trials
- Spondylo-megaepiphyseal-metaphyseal dysplasia 0 trials
- Spondyloepiphyseal dysplasia with congenital joint dislocations 0 trials
- Spondyloepiphyseal dysplasia with coronal craniosynostosis, cataracts, cleft palate, and intellectual disability 0 trials
- Spondyloepiphyseal dysplasia with punctate corneal dystrophy 0 trials
- Spondyloepiphyseal dysplasia, Holling type 0 trials
- Spondyloepiphyseal dysplasia, Kimberley type 0 trials
- Spondyloepiphyseal dysplasia, MacDermot type 0 trials
- Spondyloepiphyseal dysplasia, Reardon type 0 trials
- Spondyloepiphyseal dysplasia, kondo-fu type 0 trials
- Spondyloepiphyseal dysplasia, nishimura type 0 trials
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Spondyloepimetaphyseal dysplasia 0 trials · 4 incl. sub-types
23 sub-types
- COL2A1-related spondyloepiphyseal dysplasia 0 trials · 3 incl. sub-types Sub-types →
- Spondyloepimetaphyseal dysplasia, aggrecan type 1 trial
- Spondyloepimetaphyseal dysplasia with joint laxity 0 trials Sub-types →
- Spondyloepimetaphyseal dysplasia, Bieganski type 0 trials
- Spondyloepimetaphyseal dysplasia, Genevieve type 0 trials
- Spondyloepimetaphyseal dysplasia, Guo-Campeau type 0 trials
- Spondyloepimetaphyseal dysplasia, Handigodu type 0 trials
- Spondyloepimetaphyseal dysplasia, Irapa type 0 trials
- Spondyloepimetaphyseal dysplasia, Isidor type 0 trials
- Spondyloepimetaphyseal dysplasia, Isidor-Toutain type 0 trials
- Spondyloepimetaphyseal dysplasia, Krakow type 0 trials
- Spondyloepimetaphyseal dysplasia, Li-Shao-Li type 0 trials
- Spondyloepimetaphyseal dysplasia, Maroteaux type 0 trials
- Spondyloepimetaphyseal dysplasia, Missouri type 0 trials
- Spondyloepimetaphyseal dysplasia, PAPSS2 type 0 trials
- Spondyloepimetaphyseal dysplasia, Shohat type 0 trials
- Spondyloepimetaphyseal dysplasia, Strudwick type 0 trials
- Spondyloepimetaphyseal dysplasia, di rocco type 0 trials
- Spondyloepimetaphyseal dysplasia, matrilin-3 type 0 trials
- Spondyloepimetaphyseal dysplasia, sponastrime type 0 trials
- Spondyloepimetaphyseal dysplasia-abnormal dentition syndrome 0 trials
- Spondyloepimetaphyseal dysplasia-hypotrichosis syndrome 0 trials
- Spondyloepimetaphyseal dysplasia-short limb-abnormal calcification syndrome 0 trials
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Blount disease 2 trials
2 sub-types
- Blount disease, infantile 1 trial
- Blount disease, adolescent 0 trials
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Diastrophic dysplasia 2 trials
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Mesomelic dysplasia 0 trials · 2 incl. sub-types
6 sub-types
- Langer mesomelic dysplasia 2 trials
- Mesomelic dwarfism, Nievergelt type 0 trials
- Mesomelic dwarfism, Reinhardt-Pfeiffer type 0 trials
- Mesomelic dysplasia, Kantaputra type 0 trials Sub-types →
- Mesomelic dysplasia, Savarirayan type 0 trials
- Upper limb mesomelic dysplasia 0 trials
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Neonatal osteosclerotic dysplasia 0 trials · 2 incl. sub-types
5 sub-types
- Desmosterolosis 2 trials
- Caffey disease 0 trials
- Chondrodysplasia Blomstrand type 0 trials
- Dysplastic cortical hyperostosis 0 trials Sub-types →
- Lethal osteosclerotic bone dysplasia 0 trials
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Cleidocranial dysplasia 1 1 trial
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Midface dysplasia 1 trial
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Pseudoachondroplasia 1 trial
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Akaba Hayasaka syndrome 0 trials
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Boomerang dysplasia 0 trials
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Desbuquois dysplasia 0 trials
2 sub-types
- Desbuquois dysplasia 1 0 trials
- Desbuquois dysplasia 2 0 trials
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Fairbank disease 0 trials
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Kashin-Beck disease 0 trials
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Kniest dysplasia 0 trials
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Leri-Weill dyschondrosteosis 0 trials
1 sub-type
- Madelung deformity 0 trials Sub-types →
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Pyle disease 0 trials
2 sub-types
- Chondrodysplasia calcificans Metaphysealis 0 trials
- Metaphyseal chondrodysplasia 0 trials
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Schmid metaphyseal chondrodysplasia 0 trials
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Acheiropody 0 trials
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Achondrogenesis 0 trials
5 sub-types
- Achondrogenesis type IA 0 trials
- Achondrogenesis type IB 0 trials
- Achondrogenesis type II 0 trials
- Acromesomelic dysplasia 2A 0 trials
- Hypochondrogenesis 0 trials
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Acrocapitofemoral dysplasia 0 trials
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Acromesomelic dysplasia 0 trials
8 sub-types
- Osebold-Remondini syndrome 0 trials
- Acromesomelic dysplasia 1, Maroteaux type 0 trials
- Acromesomelic dysplasia 2A 0 trials
- Acromesomelic dysplasia 2B 0 trials
- Acromesomelic dysplasia 2C, Hunter-Thompson type 0 trials
- Acromesomelic dysplasia 3 0 trials
- Acromesomelic dysplasia 4 0 trials
- Acromesomelic dysplasia, Campailla Martinelli type 0 trials
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Atelosteogenesis 0 trials
3 sub-types
- Atelosteogenesis type I 0 trials
- Atelosteogenesis type II 0 trials
- Atelosteogenesis type III 0 trials
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Bone dysplasia, lethal Holmgren type 0 trials
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Brachyolmia 0 trials
3 sub-types
- Autosomal dominant brachyolmia 0 trials
- Autosomal recessive brachyolmia 0 trials Sub-types →
- Brachyolmia, Maroteaux type 0 trials
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Campomelic dysplasia 0 trials
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Cleidocranial dysplasia 2 0 trials
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Fibrochondrogenesis 0 trials
2 sub-types
- Fibrochondrogenesis 1 0 trials
- Fibrochondrogenesis 2 0 trials
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Lethal Kniest-like dysplasia 0 trials
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Lethal chondrodysplasia, Seller type 0 trials
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Linkeropathy 0 trials
3 sub-types
- Desbuquois dysplasia 2 0 trials
- Spondylo-ocular syndrome 0 trials
- Spondylodysplastic Ehlers-Danlos syndrome 0 trials
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Mesomelia-synostoses syndrome 0 trials
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Multiple epiphyseal dysplasia 0 trials
10 sub-types
- Epiphyseal dysplasia, multiple, 7 0 trials
- Multiple epiphyseal dysplasia due to collagen 9 anomaly 0 trials Sub-types →
- Multiple epiphyseal dysplasia type 1 0 trials
- Multiple epiphyseal dysplasia type 4 0 trials
- Multiple epiphyseal dysplasia type 5 0 trials
- Multiple epiphyseal dysplasia, Al-Gazali type 0 trials
- Multiple epiphyseal dysplasia, Beighton type 0 trials
- Multiple epiphyseal dysplasia, Lowry type 0 trials
- Multiple epiphyseal dysplasia, with miniepiphyses 0 trials
- Multiple epiphyseal dysplasia, with severe proximal femoral dysplasia 0 trials
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Pycnodysostosis 0 trials
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Pyknoachondrogenesis 0 trials
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Schneckenbecken dysplasia 0 trials
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Thanatophoric dysplasia 0 trials
4 sub-types
- Kozlowski Warren Fisher syndrome 0 trials
- Thanatophoric dysplasia type 1 0 trials
- Thanatophoric dysplasia type 2 0 trials Sub-types →
- Thanatophoric dysplasia, Glasgow variant 0 trials
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Ulna metaphyseal dysplasia syndrome 0 trials
Most studied deeper sub-types
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A common supplement may shield bones in kidney disease — a trial puts it to the test
Disease control Stopped earlyThis pilot trial investigates whether potassium citrate can improve bone quality and strength in adults and children with chronic kidney disease. Participants take either potassium citrate or a placebo for six months, along with blood and urine tests and advanced bone scans. The …
Phase 2/3 • Sponsor: Albert Einstein College of Medicine • Aim: Disease control
Last updated Jul 30, 2026 00:00 UTC
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Experimental achondroplasia drug trial halted early
Disease control Stopped earlyThis study tested an experimental drug called SAR442501 in children with achondroplasia, a common form of dwarfism. The goal was to see if the drug was safe and could improve growth. However, the trial was stopped early after enrolling only 16 children, so we have very little inf…
Phase 2 • Sponsor: Sanofi • Aim: Disease control
Last updated Jun 27, 2026 14:02 UTC
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Could a common cholesterol drug protect bones and hearts after spinal injury?
Disease control Stopped earlyThis study tested whether the statin drug rosuvastatin, taken daily with supplements, could improve bone density and reduce heart disease risk in adults with long-term spinal cord injury. Only 8 people enrolled before the trial was stopped early. Participants received either rosu…
Phase 2 • Sponsor: Dr. B. Catharine. Craven • Aim: Disease control
Last updated Jun 27, 2026 12:07 UTC
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Experimental drug for brittle bones tested in small trial
Disease control Stopped earlyThis early-stage trial tested a single dose of a drug called SAR439459 in 16 adults with osteogenesis imperfecta (brittle bone disease). The drug aims to block a protein that may weaken bones. The study focused on safety and how the drug moves through the body, but it was termina…
Phase 1 • Sponsor: Sanofi • Aim: Disease control
Last updated Jun 26, 2026 16:39 UTC
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Scientists dive into rare cholesterol disorders to uncover clues
Knowledge-focused Stopped earlyThis study looks at rare genetic disorders where the body can't make cholesterol properly, which can cause birth defects and learning problems. Researchers collect blood, urine, and tissue samples from affected people and their families to learn more about these conditions. The g…
Sponsor: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) • Aim: Knowledge-focused
Last updated Aug 14, 2026 00:00 UTC
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Elderly arthritis study reveals hidden health risks
Knowledge-focused Stopped earlyThis study aimed to understand how age influences serious health issues like infections, cancer, heart disease, and bone fractures in people with rheumatoid arthritis. Researchers compared patients over 65 with younger adults (18-50) who had the same disease. The study was stoppe…
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:59 UTC
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HIV drugs may weaken bones: new study investigates
Knowledge-focused Stopped earlyThis study looked at bone density in HIV-positive men to see if antiretroviral drugs cause bone thinning. Researchers compared men starting HIV treatment with those not yet on therapy over two years. The goal was to understand why bone loss is more common in HIV patients.
Sponsor: University Hospital, Strasbourg, France • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:51 UTC