Osteoarthritis, toe
MONDO:0006631Osteoarthritis of the foot generally affects the joint at the base of your big toe. It can cause your toe to: - become stiff over time, which can make it difficult and painful to walk – this is called hallux rigidus - become bent, which can lead to painful bunions (bony lumps at the base of your big toe) – this is called hallux valgus. Osteoarthritis of the mid-foot is also quite common, especially in older people, and may cause an obvious bony swelling (osteophyte) on the top of your mid-foot. Ankle osteoarthritis is least common and may cause your heel to move to an unusual angle.
45 clinical trials for this condition and its sub-types, 9 tagged with Osteoarthritis, toe itself.
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New toe implant aims to ease arthritis pain without fusion
Disease control Recruiting nowThis study is testing a new synthetic implant for the big toe joint in people with arthritis. The implant replaces the damaged joint surface to reduce pain and improve function. About 20 adults aged 21-75 with moderate to severe arthritis will be enrolled and followed for safety …
Sponsor: Hyalex Orthopaedics, Inc. • Aim: Disease control
Last updated Jun 27, 2026 12:10 UTC
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New thumb implant surgery tested against standard care
Disease control Recruiting nowThis study compares the usual surgery for thumb arthritis to a newer procedure that implants donated tissue at the base of the thumb. Researchers will track hand function and pain in 200 adults for one year after surgery. The goal is to see if the new approach leads to better rec…
Sponsor: Columbia University • Aim: Disease control
Last updated Jun 27, 2026 12:05 UTC
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New dissolvable screws could spare patients a second surgery
Disease control Recruiting nowThis study is testing special screws that dissolve over time, used in foot and ankle surgeries for fractures, realignments, or joint fusions. The screws are meant to hold bones together while they heal, then safely absorb into the body. Researchers will follow 125 adults for 4 ye…
Sponsor: Inion Oy • Aim: Disease control
Last updated Jun 27, 2026 11:00 UTC
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Mind over ankle: brain training may ease arthritis pain
Symptom relief Recruiting nowThis study tests whether adding a special brain-training technique called graded motor imagery to standard exercise can help people with foot or ankle osteoarthritis feel less pain and move better. Twenty-four adults with confirmed osteoarthritis will be randomly assigned to eith…
Sponsor: Alanya Alaaddin Keykubat University • Aim: Symptom relief
Last updated Jun 27, 2026 09:05 UTC