Ossification of the posterior longitudinal ligament of the spine

MONDO:0011230

A disorder characterized by benign depositions of calcium in the posterior longitudinal ligament. Signs and symptoms result from the compression of nerve roots and include motor and sensory disturbances in the lower and upper extremities, and pain in the neck and arms.

Also known as: OPLL, ossification of Posterior longitudinal ligament, ossification of the POSTERIOR longitudinal ligament of spine

1 clinical trial for this condition and its sub-types, 1 tagged with Ossification of the posterior longitudinal ligament of the spine itself.

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Where it sits in the disease tree

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Part of

↑ Skeletal system disorder (9737) ↑ Hereditary disorder of connective tissue (1314)

Including sub-types (1) Tagged with Ossification of the posterior longitudinal ligament of the spine (1)

Not yet finished but already full! 1

Front vs back surgery: which is better for stiff spine condition?

Disease control Ongoing

This study compares two surgical approaches for severe ossification of the posterior longitudinal ligament (OPLL), a condition where a ligament in the spine hardens and presses on the spinal cord. One surgery (ACAF) goes through the front of the neck to remove the hardened ligame…

Sponsor: Shanghai Changzheng Hospital • Aim: Disease control

Last updated Jun 27, 2026 12:34 UTC

Ossification of the posterior longitudinal ligament of the spine

Where it sits in the disease tree

Front vs back surgery: which is better for stiff spine condition?