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Optic atrophy
MONDO:0003608A disorder characterized by loss of optic nerve fibers. It may be inherited or acquired. Acquired causes include ischemia, optic nerve neuropathy, glaucoma, trauma, radiation, brain tumors, and multiple sclerosis. It leads to vision disturbances.
Also known as: atrophy of optic disk
29 clinical trials for this condition and its sub-types, 4 tagged with Optic atrophy itself.
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Sub-types of Optic atrophy
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Primary optic atrophy 0 trials · 23 incl. sub-types
1 sub-type
- Hereditary optic atrophy 6 trials · 23 incl. sub-types Sub-types →
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Glaucomatous atrophy of optic disk 0 trials
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Partial optic atrophy 0 trials
Most studied deeper sub-types
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Could vitamin B3 save sight in rare genetic blindness?
Disease control Not yet recruitingThis early study tests whether high-dose vitamin B3 (nicotinamide) can help preserve or improve vision in people with Leber's hereditary optic neuropathy (LHON), a rare genetic disease that causes sudden vision loss. Researchers will give 13 participants 2 grams of vitamin B3 dai…
Phase 1 • Sponsor: University Hospital, Angers • Aim: Disease control
Last updated Jun 27, 2026 08:05 UTC
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Are these two eye diseases actually the same? new study aims to find out
Knowledge-focused Not yet recruitingThis study will look back at medical records of 45 people with either Wolfram syndrome or a related eye condition caused by changes in the WFS1 gene. Researchers want to see if these two conditions are truly different by comparing vision loss over time and other health problems. …
Sponsor: Hôpital Necker-Enfants Malades • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:10 UTC