Opioid-induced constipation
MONDO:0100187A constipation disorder caused by use of opioids. OIC may present immediately when a patient takes the opioid, or it may present gradually during opioid therapy.
Also known as: OIC
15 clinical trials for this condition and its sub-types, 13 tagged with Opioid-induced constipation itself.
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AI stethoscope aims to spot hidden heart and lung problems in children
Diagnosis Recruiting nowThis trial is developing an AI-powered device that listens to children's heart, breath, and bowel sounds to identify signs of common diseases like congenital heart disease, bronchopneumonia, and abdominal issues. It will involve 30,000 children aged 0-18, some with these conditio…
Sponsor: Xinhua Hospital, Shanghai Jiao Tong University School of Medicine • Aim: Diagnosis
Last updated Aug 14, 2026 00:00 UTC
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New hope for kids on painkillers: constipation relief drug under study
Symptom relief Recruiting nowThis study is testing a medicine called naldemedine to help children who get constipated from taking opioids (strong painkillers). About 24 children with cancer or other pain conditions will receive a single dose of the drug. Researchers will measure how the drug moves through th…
Phase 1/2 • Sponsor: Shionogi • Aim: Symptom relief
Last updated Jul 30, 2026 00:00 UTC
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New hope for cancer patients suffering from painkiller side effects
Symptom relief Recruiting nowThis study tests a medicine called naldemedine for constipation caused by opioids (strong painkillers) in people with cancer. About 100 adults with cancer who take opioids and still have constipation despite laxatives will receive naldemedine. Researchers will measure how well it…
Sponsor: Professor Monique A. H. Steegers • Aim: Symptom relief
Last updated Jun 27, 2026 08:08 UTC
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2000 patients join effort to unravel mysteries of stomach and gut disorders
Knowledge-focused Recruiting nowThis study is following 2000 adults with functional digestive disorders like irritable bowel syndrome, dyspepsia, and constipation. Researchers will collect medical data and biological samples (biopsies, blood, urine, stool) during routine care. The goal is to find markers that c…
Sponsor: University Hospital, Rouen • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:09 UTC