Ocular hypertension

This trial tests a support program for adults with glaucoma who struggle to take their eye drops regularly or attend clinic visits. Participants identify their main barrier, such as forgetfulness or difficulty using drops, and receive matching help like education, reminders, or t…

This trial compares two surgical implants—the Baerveldt Glaucoma Implant and the Paul Glaucoma Implant—in people with glaucoma that is not well controlled by eye drops. Both devices are tiny tubes placed in the eye to drain fluid and lower pressure. The study will track which imp…

This study tests an experimental drug called REGN22530 in people with primary open angle glaucoma or ocular hypertension. The drug is designed to block a protein in the eye that causes fluid buildup and high pressure. Researchers are checking for side effects, how the drug moves …

This early study tests a small ring placed in the eye that slowly releases the drug bimatoprost to lower eye pressure in people with glaucoma or ocular hypertension. The ring is implanted during a quick surgery and may work for up to 3 years. The trial includes 24 adults and comp…

This Phase 3 trial tests a new eye drop, DNN.31.19.026, against a standard treatment (Cosopt) for people with high eye pressure or open-angle glaucoma. About 336 adults will use the drops twice daily for 56 days. The main goal is to see if the new drop lowers eye pressure better …

This study tests a new laser treatment called DSLT for people with high eye pressure or open-angle glaucoma who have already had a similar laser (SLT). The DSLT laser does not touch the eye, which may make it faster and more comfortable. Researchers want to see how well it lowers…

This study looks at 60 adults with high eye pressure or early open-angle glaucoma to see if combining advanced eye scans and vision tests can detect damage sooner. Participants will have standard eye exams plus special imaging of the optic nerve. The goal is to improve how doctor…

This study tests a device called Nanodropper that attaches to eye drop bottles and makes each drop smaller. Many glaucoma patients have trouble getting drops into their eyes or use too much, wasting medication. The trial will see if the device helps patients finish their bottles …

Anti-VEGF injections treat conditions like diabetic macular edema, age-related macular degeneration, and retinal vein occlusion by adding fluid inside the eye, which can briefly raise eye pressure. This observational study at Assiut University follows 50 adults receiving these ro…

This trial tests whether eplerenone, a drug already approved for other conditions, lowers eye pressure in healthy adults. Researchers will compare eplerenone with a placebo in a crossover design, where each participant takes both treatments at different times. Eye pressure is mea…

This study will screen over 7,000 adults aged 40+ living in affordable housing in New York City for undiagnosed high blood pressure and glaucoma. Participants who need follow-up care will be randomly assigned to receive text message reminders or usual care. The goal is to see if …

This study will measure eye pressure in one person with mild keratoconus before and one month after corneal cross linking. The goal is to see how the treatment changes eye pressure using a special device called Corvis CT. This is an observational study, not a treatment trial.

This study will measure how eye pressure changes after common laser vision correction surgeries like PRK, LASIK, and femtosecond laser. Researchers will compare two measurement methods—Corvis CT and the standard applanation tonometer—in 50 people aged 19 to 35 with mild to modera…