NF2-related schwannomatosis
MONDO:0007039A tumor-prone disorder characterized by the development of multiple schwannomas and meningiomas.
Also known as: acoustic neurofibromatosis, NF2, NF2-related schwannomatosis, SWNV, bilateral acoustic neurofibromatosis, central neurofibromatosis, full NF2, full neurofibromatosis type 2
52 clinical trials for this condition and its sub-types, 21 tagged with NF2-related schwannomatosis itself.
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Could a cancer drug shrink NF2 tumors?
Disease control CompletedThis phase 2 trial tested the drug crizotinib in 12 people with neurofibromatosis type 2 (NF2) who had growing tumors in the ear area called vestibular schwannomas. Participants took crizotinib pills daily for up to 12 months. The main goal was to see if the drug could shrink the…
Phase 2 • Sponsor: University of Alabama at Birmingham • Aim: Disease control
Last updated Jun 27, 2026 11:01 UTC
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Smart glasses could help deafness in rare nerve disorder
Symptom relief CompletedThis study looks at whether auto-captioning glasses are easy and helpful for adults with NF2-related schwannomatosis who have hearing loss. Eighteen participants will use the glasses for 12 weeks and report their experience through surveys and interviews. The goal is to see if th…
Sponsor: Massachusetts General Hospital • Aim: Symptom relief
Last updated Aug 27, 2026 00:00 UTC
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Teens with NF try video coaching to boost mood and health
Symptom relief CompletedThis study tested two 8-week stress management programs delivered via secure video calls for 196 adolescents aged 12–17 with neurofibromatosis (NF1 or NF2). The goal was to see if these programs could improve emotional, social, and physical quality of life. Both programs taught c…
Sponsor: Massachusetts General Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 13:07 UTC
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Video-Based stress program aims to ease life with neurofibromatosis
Symptom relief CompletedThis study tested two stress and symptom management programs for adults with neurofibromatosis (NF1, NF2, or schwannomatosis). The programs were delivered through live videoconferencing over 8 weekly sessions. Researchers measured changes in quality of life and emotional well-bei…
Sponsor: Massachusetts General Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 08:07 UTC