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Neurodevelopmental disorder with involuntary movements

MONDO:0060491

Also known as: GNAO1-related developmental delay-seizures-movement disorder spectrum, GNAO1-related spectrum, neurodevelopmental disorder with involuntary movements, NEDIM

2 clinical trials for this condition and its sub-types, 2 tagged with Neurodevelopmental disorder with involuntary movements itself.

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Where it sits in the disease tree

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Part of

↑ Mendelian neurodevelopmental disorder (208)

Including sub-types (2) Tagged with Neurodevelopmental disorder with involuntary movements (2)

Trials to join now! 1 Completed 1

Could a common mineral ease rare genetic disorder? zinc trial shows promise

Disease control Completed

This pilot trial tested whether taking oral zinc every day for 6 months is safe and doable for people with GNAO1 disorders, a rare genetic condition that causes movement problems, seizures, and developmental delays. 13 participants aged 6 months to 30 years took zinc acetate. The…

Phase 2 • Sponsor: Children's University Hospital Cologne, Germany • Aim: Disease control

Last updated Jun 27, 2026 09:01 UTC