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Neurodevelopmental disorder with involuntary movements

MONDO:0060491

Also known as: GNAO1-related developmental delay-seizures-movement disorder spectrum, GNAO1-related spectrum, neurodevelopmental disorder with involuntary movements, NEDIM

2 clinical trials for this condition and its sub-types.

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Broader categories

Disease (717) Nervous system disorder (243) Hereditary disease (188) Neurodevelopmental disorder (154) Human disease (15) Hereditary neurological disease (6) Disease of genetic or genomic mechanism (2) Disease by body system or component (0) Disease by etiologic mechanism (0) Mendelian neurodevelopmental disorder (0)
Trials to join now! 1 Completed 1
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  • New hope for kids with rare GNAO1 epilepsy: experimental drug trial launches

    Disease control Recruiting now

    This study tests an experimental drug called ASO-GNAO1 (Tianasen) in 5 children aged 1 to 14 with a specific GNAO1 gene mutation that causes severe epilepsy and movement problems. The drug is given via spinal injections over 12 months to see if it can reduce seizures and improve …

    Phase 1/2 • Sponsor: Pirogov Russian National Research Medical University • Aim: Disease control

    Last updated Jun 27, 2026 08:13 UTC

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