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Neurodevelopmental disorder with involuntary movements

MONDO:0060491

Also known as: GNAO1-related developmental delay-seizures-movement disorder spectrum, GNAO1-related spectrum, neurodevelopmental disorder with involuntary movements, NEDIM

2 clinical trials for this condition and its sub-types.

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Broader categories

Disease (717) Nervous system disorder (243) Hereditary disease (188) Neurodevelopmental disorder (154) Human disease (15) Hereditary neurological disease (6) Disease of genetic or genomic mechanism (2) Disease by body system or component (0) Disease by etiologic mechanism (0) Mendelian neurodevelopmental disorder (0)
Trials to join now! 1 Completed 1
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  • Could a common mineral ease rare genetic disorder? zinc trial shows promise

    Disease control Completed

    This pilot trial tested whether taking oral zinc every day for 6 months is safe and doable for people with GNAO1 disorders, a rare genetic condition that causes movement problems, seizures, and developmental delays. 13 participants aged 6 months to 30 years took zinc acetate. The…

    Phase 2 • Sponsor: Children's University Hospital Cologne, Germany • Aim: Disease control

    Last updated Jun 27, 2026 09:01 UTC

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