Nail infection

This early-stage trial is testing a highly concentrated liquid antifungal, luliconazole 10% (SKX-16), applied daily to all ten toenails for 29 days in adults with moderate to severe toenail fungus. The main goals are to see how much of the drug is absorbed into the body, and whet…

This completed study tested two topical serums for treating toenail fungus (onychomycosis). 44 adults with mild to moderate infection applied one or both serums daily for 112 days. Researchers measured the change in healthy nail area using photos. The goal was to see if using bot…

This study tested two treatments for toenail fungus in 27 Asian adults: a light-activated dye (methylene blue photodynamic therapy) and a medicated nail polish (amorolfine). The goal was to see which worked better and was safer. Participants received either the light treatment or…

This study tested a light therapy device called ToeFX for mild to moderate toenail fungus. 126 people with fungal infection in one big toenail used the device. Researchers measured new clear nail growth after 12 months to see if the treatment worked and was safe.

This study tested a special gel, CGB-400, on 15 adults with toenail fungus. The goal was to see if the gel could clear the fungus and make the nails look better. Participants applied the gel for 12 weeks, with follow-up visits to check progress.