Myxoid/round cell liposarcoma
MONDO:0020561Myxoid/round cell liposarcoma (MRCLS) is a type of liposarcoma (LS) mostly located in the limbs, with a variable behavior depending on the histological subtype. Both myxoid and round cell are distinct histological subtypes of LS.
Also known as: MRCLS, myxoid/round-cell liposarcoma
2840 clinical trials for this condition and its sub-types, 13 tagged with Myxoid/round cell liposarcoma itself.
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Sub-types of Myxoid/round cell liposarcoma
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Myxoid liposarcoma 15 trials
1 sub-type
- Ovarian myxoid liposarcoma 0 trials
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Round cell liposarcoma 3 trials
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Designer immune cells take on rare sarcomas
Disease control CompletedThis phase 2 trial tests a personalized cell therapy called Lete-Cel in 7 people with advanced synovial sarcoma or myxoid/round cell liposarcoma that has not been treated before. Participants receive their own immune cells that have been engineered to recognize and attack their c…
Phase 2 • Sponsor: USWM, LLC (dba US WorldMeds) • Aim: Disease control
Last updated Sep 04, 2026 00:00 UTC
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Engineered immune cells take on rare sarcomas in new trial
Disease control CompletedThis phase 2 trial tests a treatment called Lete-Cel, which uses a patient's own immune cells that have been specially trained to attack cancer cells. It is for people with advanced synovial sarcoma or myxoid/round cell liposarcoma whose tumors have a specific marker (NY-ESO-1) a…
Phase 2 • Sponsor: USWM CT, LLC • Aim: Disease control
Last updated Aug 15, 2026 00:00 UTC
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New combo therapy shows promise for rare liposarcoma
Disease control CompletedThis phase 2 study tested whether adding pioglitazone (a diabetes drug) to trabectedin (a chemotherapy) could help shrink or control liposarcoma, a rare cancer of fat tissue. The study included 10 patients whose tumors had stopped growing but not shrunk with trabectedin alone. Re…
Phase 2 • Sponsor: Mario Negri Institute for Pharmacological Research • Aim: Disease control
Last updated Jun 27, 2026 09:06 UTC
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Personalized chemo shows promise against rare sarcomas
Disease control CompletedThis Phase 3 trial tested whether giving chemotherapy based on the specific type of soft tissue sarcoma works better than a one-size-fits-all approach. 550 adults with high-risk sarcomas in the arms or trunk were randomly assigned to standard chemo or a chemo regimen matched to t…
Phase 3 • Sponsor: Italian Sarcoma Group • Aim: Disease control
Last updated Jun 27, 2026 07:58 UTC