Myxofibrosarcoma
MONDO:0019202A malignant fibroblastic neoplasm arising from the soft tissue. It is characterized by the presence of spindle-shaped cells, cellular pleomorphism, thin-walled blood vessels, fibrous septa, and myxoid stroma.
Also known as: fibromyxosarcoma, myxofibrosarcoma, myxoid MFH, myxoid fibrous histiocytoma, myxoid malignant fibrous histiocytoma, MFS
2826 clinical trials for this condition and its sub-types, 21 tagged with Myxofibrosarcoma itself.
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Virus and radiation combo takes aim at tough sarcomas
Disease control OngoingThis phase 2 trial tests whether injecting a modified herpes virus (TVEC) directly into tumors, combined with radiation therapy before surgery, can shrink advanced soft tissue sarcomas. The study enrolled 2 adults with specific sarcoma types that could not be removed with clear m…
Phase 2 • Sponsor: John Rieth • Aim: Disease control
Last updated Jul 19, 2026 00:00 UTC
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Cancer-Killing virus paired with immunotherapy shows promise in sarcoma trial
Disease control OngoingThis phase 2 study tests a combination of two drugs—talimogene laherparepvec (T-VEC), a virus that attacks cancer cells, and pembrolizumab, an immunotherapy that helps the immune system fight cancer—in 41 adults with advanced sarcoma that has spread or cannot be removed by surger…
Phase 2 • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Disease control
Last updated Jul 19, 2026 00:00 UTC
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Experimental combo aims to boost immune attack on sarcoma before surgery
Disease control OngoingThis early-phase study tests the safety of combining two immunotherapy drugs—nivolumab and BO-112—given before surgery for soft tissue sarcoma that can be removed. About 14 adults with certain sarcoma types will receive these drugs to see if they help the immune system fight the …
Phase 1 • Sponsor: Jonsson Comprehensive Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 11:00 UTC