Myofibroma
MONDO:0006312A benign, localized, nodular and well-circumscribed neoplasm usually seen as a congenital neoplasm or in the first year of life. It is characterized by a biphasic growth pattern and is composed of small, undifferentiated mesenchymal cells associated with branching thin-walled vessels and more mature neoplastic spindle cells with abundant eosinophilic cytoplasm in a collagenous stroma.
Also known as: myofibroma, myofibroma (morphologic abnormality), infantile hemangiopericytoma
1447 clinical trials for this condition and its sub-types, 17 tagged with Myofibroma itself.
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New study tests best method to cut bleeding in fibroid surgery
Symptom relief CompletedThis study looked at 120 women having open surgery for uterine fibroids to see which method best reduces bleeding. Doctors compared using a tourniquet, clamping the uterine artery, or no compression at all. The goal is to find the safest way to control blood loss and improve reco…
Sponsor: Yuzuncu Yil University • Aim: Symptom relief
Last updated Jun 27, 2026 12:24 UTC
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Supplements before fibroid surgery show promise in small study
Symptom relief CompletedThis pilot study tested whether taking a combination of EGCG (from green tea), vitamin D, and D-chiro-inositol for three months before hysteroscopic myomectomy improves surgical outcomes. 90 women with uterine fibroids were divided into two groups: one received the supplements be…
Sponsor: Centro di Ricerca Clinica Salentino • Aim: Symptom relief
Last updated Jun 27, 2026 08:01 UTC
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Uterine scar tissue after fibroid surgery: who is at risk?
Knowledge-focused CompletedThis study looks at how often women develop intrauterine adhesions (scar tissue inside the uterus) after having fibroids removed through laparoscopic or open surgery. Researchers will check for adhesions using a small camera inserted into the uterus three months after surgery. Th…
Sponsor: Università degli Studi dell'Insubria • Aim: Knowledge-focused
Last updated Aug 19, 2026 00:00 UTC
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Fertility after fibroid embolization: new data from 46 women
Knowledge-focused CompletedThis study looked back at 46 women who had a procedure called uterine artery embolization to treat fibroids. The goal was to see how often women later had a baby and what pregnancy complications occurred. The researchers reviewed medical records from one hospital in France to gat…
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:05 UTC
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New vaginal surgery may ease brain pressure during hysterectomy
Knowledge-focused CompletedThis study compared two types of hysterectomy surgery: vNOTES (done through the vagina) and TLH (done through small belly cuts). Researchers measured optic nerve sheath diameter, an indirect sign of brain pressure, in 66 women. The goal was to see if vNOTES causes less pressure o…
Sponsor: Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:08 UTC
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Fibroid location linked to changes in uterine blood flow
Knowledge-focused CompletedThis study looked at how the location of uterine fibroids affects blood flow in the uterine artery. Researchers used ultrasound to measure blood flow in 185 women with fibroids and compared results based on fibroid location. They found that fibroids located within the uterine mus…
Sponsor: Bakirkoy Dr. Sadi Konuk Research and Training Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:51 UTC
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Surgeons try High-Tech goggles to spot hidden tumors during keyhole surgery
Knowledge-focused CompletedThis completed study tested whether augmented reality (AR) can help surgeons during laparoscopic surgery for uterine fibroids or adenomyosis. AR overlays images from pre-surgery scans onto the live video feed, potentially making it easier to see and remove benign tumors. Forty pa…
Sponsor: University Hospital, Clermont-Ferrand • Aim: Knowledge-focused
Last updated Jun 26, 2026 16:26 UTC