Multiple endocrine neoplasia

MONDO:0017169

Multiple endocrine neoplasia (MEN) is a group of rare inherited cancer syndromes characterized by the development of two or more endocrine gland tumors, sometimes with tumor development in other tissues or organs.

Also known as: MEN, men syndrome, men syndromes, multiple endocrine adenomatosis, multiple endocrine neoplasia, multiple endocrine neoplasia syndrome, multiple endocrine neoplasia syndrome(s)

93 clinical trials for this condition and its sub-types, 7 tagged with Multiple endocrine neoplasia itself.

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Where it sits in the disease tree

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Part of

↑ Neurocristopathy (1555) ↑ Hereditary neoplastic syndrome (731) ↑ Multiple polyglandular tumor (62)

Sub-types of Multiple endocrine neoplasia

Multiple endocrine neoplasia type 1 34 trials
Multiple endocrine neoplasia type 2 4 trials · 30 incl. sub-types
3 sub-types
- Familial medullary thyroid carcinoma 23 trials
- Multiple endocrine neoplasia type 2A 4 trials
- Multiple endocrine neoplasia type 2B 2 trials
Multiple endocrine neoplasia type 4 0 trials

Including sub-types (93) Tagged with Multiple endocrine neoplasia (7)

Trials to join now! 32 Not yet recruiting 6 Not yet finished but already full! 30 Completed 24 Terminated 1

Old arthritis drug tested against rare tumor syndrome – but trial stalls

Disease control Stopped early

This study tested leflunomide, a drug used for rheumatoid arthritis, in 3 adults with MEN1 syndrome—a genetic condition that raises the risk of multiple tumors. The goal was to see if 6 months of daily leflunomide could shrink or stabilize tumors. However, the trial was terminate…

Sponsor: University Hospital, Basel, Switzerland • Aim: Disease control

Last updated Jun 27, 2026 09:00 UTC

Multiple endocrine neoplasia

Where it sits in the disease tree

Old arthritis drug tested against rare tumor syndrome – but trial stalls