Multiple cutaneous and mucosal venous malformations

MONDO:0010842

Mucocutaneous venous malformations (VMCMs) are hereditary vascular malformations characterized by the presence of small, multifocal, bluish-purple venous lesions involving the skin and mucosa.

Also known as: VMCM, cutaneous and mucosal venous malformation, VENOUS malformations, multiple cutaneous and mucosal, Vmcm1, mucocutaneous venous malformations

1 clinical trial for this condition and its sub-types, 1 tagged with Multiple cutaneous and mucosal venous malformations itself.

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Where it sits in the disease tree

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Part of

↑ Vascular disorder (10696) ↑ Autosomal dominant disease (699)

Including sub-types (1) Tagged with Multiple cutaneous and mucosal venous malformations (1)

Not yet finished but already full! 1

New gel could treat painful skin vein bumps

Disease control Ongoing

This phase 2 trial tests a gel containing sirolimus (PTX-022) on 15 people with visible venous malformations on the skin. The goal is to see if the gel is safe and can improve the appearance and symptoms of these abnormal veins. Participants apply the gel daily for 12 weeks, and …

Phase 2 • Sponsor: Palvella Therapeutics, Inc. • Aim: Disease control

Last updated Jun 27, 2026 12:01 UTC

Multiple cutaneous and mucosal venous malformations

Where it sits in the disease tree

New gel could treat painful skin vein bumps