Monoclonal paraproteinemia disease
MONDO:0002274A disease characterized by the presence of excessive amounts of paraprotein or single monoclonal gammaglobulin in the blood. It is usually due to an underlying immunoproliferative disorder or hematologic neoplasms, especially multiple myeloma.
Also known as: paraproteinaemia
3 clinical trials for this condition and its sub-types, 2 tagged with Monoclonal paraproteinemia disease itself.
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Can a cancer drug rescue kidneys harmed by rogue antibodies?
Disease control Recruiting nowResearchers are testing whether the drug daratumumab can treat kidney diseases caused by monoclonal gammopathy of renal significance (MGRS), a group of conditions where abnormal antibody proteins damage the kidneys. The trial enrolls 30 adults with biopsy-confirmed MGRS. Particip…
Phase 2 • Sponsor: Helsinki University Central Hospital • Aim: Disease control
Last updated Sep 18, 2026 00:00 UTC
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Gene therapy builds Cancer-Killing cells inside you – no lab needed
Disease control Recruiting nowThis early-stage trial tests a new gene therapy called KLN-1010 for people with multiple myeloma that has come back or stopped responding to treatment. Instead of removing cells and engineering them in a lab, this therapy works inside the body to create special immune cells that …
Phase 1 • Sponsor: Kelonia Therapeutics, Inc. • Aim: Disease control
Last updated Aug 30, 2026 00:00 UTC