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Monkeypox
MONDO:0002594An infection that is caused by an Orthopoxvirus, which is transmitted by primates or rodents, and which is characterized by a prodromal syndrome of fever, chills, headache, myalgia, and lymphedema; initial symptoms are followed by a generalized papular rash that typically progresses from vesiculation through crusting over the course of two weeks.
Also known as: Monkeypox virus infection, infections, Monkeypox virus
43 clinical trials for this condition and its sub-types, 40 tagged with Monkeypox itself.
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New mpox vaccine trial launches in DRC: could it be a game changer?
Vaccine Not yet recruitingThis Phase 2 study will test a new mpox vaccine called MVA-SIBP in 180 people aged 2 to 45 in Kinshasa, DRC. Participants will receive two doses of either a low or high dose of the new vaccine, or a licensed vaccine (MVA-BN) for comparison. The goal is to check safety and how wel…
Phase 2 • Sponsor: Shanghai Institute Of Biological Products • Aim: Vaccine
Last updated Jun 27, 2026 08:00 UTC
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Can a cancer drug wake up immune cells to beat HIV-Related infections?
Disease control Not yet recruitingThis study tests a drug called Sintilimab, which is normally used for cancer, to see if it can help people with HIV who have infections that won't go away with standard treatment. The drug works by 'waking up' exhausted immune cells. Fifty adults with HIV and a hard-to-treat infe…
Phase 1/2 • Sponsor: Shanghai Public Health Clinical Center • Aim: Disease control
Last updated Jun 27, 2026 12:31 UTC
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Mpox immunity under the microscope: new study tracks lasting protection
Knowledge-focused Not yet recruitingThis study looks at how well the body remembers mpox after an infection. Researchers will measure antibodies and special immune cells in 60 people who had mpox. The goal is to understand how long protection might last and how strong it is.
Sponsor: ANRS, Emerging Infectious Diseases • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:34 UTC
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Mpox study in guinea aims to unlock secrets of virus spread and vaccine power
Knowledge-focused Not yet recruitingThis study in Guinea will follow about 992 people to understand how long the mpox virus stays in the body after infection, how it spreads to close contacts, and how well the MVA-BN vaccine protects against infection and disease. Researchers will collect samples and track particip…
Sponsor: London School of Hygiene and Tropical Medicine • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:07 UTC
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Mpox booster study aims to see how long protection lasts
Knowledge-focused Not yet recruitingThis observational study will follow 95 adults who receive a booster dose of the MVA-BN vaccine against mpox. Researchers will collect blood and other samples over two years to measure antibody and immune cell responses. The goal is to understand how long the booster's protection…
Sponsor: Institute of Tropical Medicine, Belgium • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:12 UTC