Metastatic squamous cell carcinoma
MONDO:0044907A squamous cell carcinoma which has spread from its original site of growth to another anatomic site.
Also known as: Metastatic squamous cell carcinoma
3034 clinical trials for this condition and its sub-types, 39 tagged with Metastatic squamous cell carcinoma itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →-
Lab-Grown immune cells take on head and neck cancer
Disease control CompletedThis early-phase trial tests a new approach for advanced head and neck cancer that has stopped responding to standard treatments. Doctors take a patient's own tumor-fighting immune cells (TILs), grow more of them in a lab, and give them back along with the immunotherapy drug Keyt…
Phase 1 • Sponsor: H. Lee Moffitt Cancer Center and Research Institute • Aim: Disease control
Last updated Sep 17, 2026 00:00 UTC
-
Can targeted radiation boost Immunotherapy's power against head and neck cancer?
Disease control CompletedThis trial is testing whether adding targeted radiation (SBRT) to two immunotherapy drugs, durvalumab and tremelimumab, can better control metastatic head and neck cancer. The study includes adults with this cancer that has spread, and the radiation is given between cycles of the…
Phase 1/2 • Sponsor: Centre hospitalier de l'Université de Montréal (CHUM) • Aim: Disease control
Last updated Aug 16, 2026 00:00 UTC
-
New combo therapy shows promise for tough head and neck cancers
Disease control CompletedThis phase II trial tested whether adding sorafenib to cetuximab works better than cetuximab alone for patients with advanced head and neck cancer that has come back or spread. Fifty-five adults with various types of head and neck cancer took part. The study measured how long pat…
Phase 2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jun 27, 2026 11:00 UTC
-
Experimental combo targets Hard-to-Treat head and neck cancers
Disease control CompletedThis early-phase trial tested a combination of two drugs — IRX-2 and durvalumab — in 19 people with advanced head and neck cancer that could not be cured by standard treatments. The goal was to see if the combination was safe and could boost the immune response inside tumors. The…
Phase 1 • Sponsor: H. Lee Moffitt Cancer Center and Research Institute • Aim: Disease control
Last updated Jun 27, 2026 08:02 UTC
-
New combo therapy shows promise for tough head and neck cancers
Disease control CompletedThis phase 2 trial tested a combination of a short, intense course of radiation (quad-shot) and the immunotherapy drug pembrolizumab in 21 people with advanced, recurrent, or metastatic head and neck cancer. The goal was to see if the combination could shrink tumors and be safe. …
Phase 2 • Sponsor: Wake Forest University Health Sciences • Aim: Disease control
Last updated Jun 27, 2026 07:58 UTC
-
New drug shows promise for tough head and neck cancers
Disease control CompletedThis study tested an experimental drug called ozuriftamab vedotin in 42 people with head and neck cancer that returned or spread. The goal was to see if the drug could shrink tumors and to check for side effects. Participants received the drug alone or with other treatments, and …
Phase 2 • Sponsor: BioAtla, Inc. • Aim: Disease control
Last updated Jun 27, 2026 07:51 UTC
-
New gel may cut pain and bleeding after mouth surgery
Symptom relief CompletedThis study tested whether a gel called PuraBond, applied to the surgical wound during mouth or throat surgery, can reduce pain and bleeding afterward. 73 patients were randomly assigned to receive the gel or not. Researchers measured pain levels over 30 days and tracked complicat…
Sponsor: University of Liverpool • Aim: Symptom relief
Last updated Jun 26, 2026 18:17 UTC