Metastatic carcinoma in the bone
MONDO:0024884A carcinoma that has spread to the bone from another, primary anatomic site. Bone is one of the most frequent sites of metastatic carcinoma. Common sites of origin include lung, breast, and prostate.
Also known as: metastatic carcinoma in the bone, metastatic carcinoma to the bone
3103 clinical trials for this condition and its sub-types, 107 tagged with Metastatic carcinoma in the bone itself.
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Can a radioactive injection target bone tumors? a Dose-Finding trial aims to find out
Disease control Stopped earlyThis early-stage trial is testing an experimental drug called CycloSam (153-Sm-DOTMP), a radioactive compound that delivers radiation directly to bone tumors when injected. The study aims to find the safest dose in people aged 15 to 75 with solid tumors that have spread to the bo…
Phase 1 • Sponsor: QSAM Therapeutics, Inc. • Aim: Disease control
Last updated Jul 25, 2026 00:00 UTC
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Promising prostate cancer combo trial stalls after just 7 patients
Disease control Stopped earlyThis phase II trial tested two drugs—denosumab and enzalutamide—together in men with advanced prostate cancer that no longer responds to hormone therapy and has spread to the bones. The goal was to see if the combination could slow cancer growth better than enzalutamide alone. Ho…
Phase 2 • Sponsor: Cancer Trials Ireland • Aim: Disease control
Last updated Jun 27, 2026 12:06 UTC
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Experimental drug shows promise for Hard-to-Treat prostate cancer
Disease control Stopped earlyThis phase 2 study tested the drug erdafitinib in 11 men with castration-resistant prostate cancer that had spread to the bone. The goal was to see if the drug could slow the cancer and to study bone and blood markers. The trial was terminated early, so results are limited.
Phase 2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 09:02 UTC
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Precision brain radiation aimed at easing cancer bone pain
Symptom relief Stopped earlyThis study tested whether a single, highly focused dose of radiation to a tiny part of the brain (the pituitary gland) could help relieve severe, hard-to-treat bone pain caused by cancer that has spread. Only 5 people took part, and the study was stopped early. The goal was to se…
Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins • Aim: Symptom relief
Last updated Sep 19, 2026 00:00 UTC
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Which radiotherapy plan best eases bone metastasis symptoms?
Symptom relief Stopped earlyThis study compared two ways of giving palliative radiotherapy to people with cancer that has spread to the bones. The goal was to see which method better controls nausea and vomiting caused by radiation, while also managing pain. About 160 adults with bone metastases took part, …
Sponsor: British Columbia Cancer Agency • Aim: Symptom relief
Last updated Jun 27, 2026 11:01 UTC
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Radioactive treatment for bone pain in advanced prostate cancer tested, but study stopped early
Symptom relief Stopped earlyThis study tested a radioactive drug called Sn-117m-DTPA to see if it could reduce bone pain in men with prostate cancer that had spread to their bones and no longer responded to hormone therapy. Only one person enrolled before the study was stopped. The goal was to measure pain …
Phase 2 • Sponsor: National Cancer Institute (NCI) • Aim: Symptom relief
Last updated Jun 27, 2026 07:53 UTC
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Could a blood chemical explain bone pain in breast cancer?
Knowledge-focused Stopped earlyThis study looks at whether levels of histamine, a chemical in the blood, are linked to bone pain in people with breast cancer that has spread to the bones. Researchers will collect blood samples from participants and compare histamine levels with pain scores, including in those …
Sponsor: Wake Forest University Health Sciences • Aim: Knowledge-focused
Last updated Aug 05, 2026 00:00 UTC