Malignant hypertension
MONDO:0006846Severe hypertension that is characterized by rapid onset of extremely high blood pressure and hypertension-mediated organ damage.
Also known as: MHT, accelerated-malignant hypertension, hypertensive emergency, malignant phase hypertension
13 clinical trials for this condition and its sub-types, 9 tagged with Malignant hypertension itself.
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Sub-types of Malignant hypertension
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Malignant essential hypertension 0 trials
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Malignant hypertensive renal disease 0 trials
1 sub-type
- Malignant renovascular hypertension 0 trials
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Malignant secondary hypertension 0 trials
1 sub-type
- Malignant renovascular hypertension 0 trials
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New shot aims to keep blood pressure in check after hospital discharge
Disease control Recruiting nowThis study tests a drug called tonlamarsen in adults who were recently hospitalized for dangerously high blood pressure. Participants receive either the drug or a placebo as a shot under the skin every 4 weeks. The goal is to see if tonlamarsen can lower blood pressure and reduce…
Phase 2 • Sponsor: Kardigan, Inc. • Aim: Disease control
Last updated Sep 04, 2026 00:00 UTC
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Blood test could unlock precision medicine for deadly TMA
Diagnosis Recruiting nowThis study is testing a new blood test (the HMEC test) to see if it can better identify which patients with thrombotic microangiopathy (TMA) have a specific immune system problem driving their disease. TMA is a severe condition that damages kidneys and the brain. The researchers …
Sponsor: Maastricht University Medical Center • Aim: Diagnosis
Last updated Jun 27, 2026 07:53 UTC
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Heart patients get flu shot at discharge to prevent future attacks
Prevention Recruiting nowThis study tests whether giving the flu vaccine to heart patients just before they leave the hospital can lower their risk of infections, heart problems, and death in the next 6 months. About 400 adults hospitalized for serious heart conditions will be randomly assigned to get th…
Phase 4 • Sponsor: Wroclaw Medical University • Aim: Prevention
Last updated Jun 27, 2026 13:00 UTC
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Massive study aims to rewrite the rules for malignant hypertension
Knowledge-focused Recruiting nowThis study is building a large database of 1,200 people with malignant hypertension, a severe form of high blood pressure that can damage organs quickly. Researchers will track patients for five years to learn how the disease behaves today and how doctors treat it. The goal is to…
Sponsor: Centre Hospitalier de PAU • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC