Malignant endocrine neoplasm
MONDO:0021069A malignant neoplasm affecting the endocrine glands. Representative examples include thyroid gland carcinoma, parathyroid gland carcinoma, pituitary gland carcinoma, and adrenal cortex carcinoma.
Also known as: endocrine neoplasm, Endocrine tumour, cancer of endocrine gland, endocrine cancer, endocrine gland cancer, endocrine neoplasm, malignant, malignant endocrine gland neoplasm, malignant endocrine gland tumor
5489 clinical trials for this condition and its sub-types, 17 tagged with Malignant endocrine neoplasm itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Malignant endocrine neoplasm
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Liver cancer 255 trials · 1,708 incl. sub-types
5 sub-types
- Carcinoma of liver and intrahepatic biliary tract 36 trials · 1,461 incl. sub-types Sub-types →
- Biliary tract cancer 244 trials · 618 incl. sub-types Sub-types →
- Liver sarcoma 1 trial · 10 incl. sub-types Sub-types →
- Liver lymphoma 1 trial Sub-types →
- Calcifying nested epithelial stromal tumor of the liver 0 trials
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Neuroendocrine carcinoma 106 trials · 744 incl. sub-types
12 sub-types
- Small cell carcinoma 26 trials · 542 incl. sub-types Sub-types →
- Cutaneous neuroendocrine carcinoma 78 trials
- Medullary thyroid gland carcinoma 42 trials · 53 incl. sub-types Sub-types →
- Large cell neuroendocrine carcinoma 12 trials · 31 incl. sub-types Sub-types →
- Pancreatic endocrine carcinoma 12 trials Sub-types →
- Malignant adrenal gland pheochromocytoma 11 trials
- Liver neuroendocrine carcinoma 3 trials Sub-types →
- Thymic neuroendocrine carcinoma 3 trials Sub-types →
- Goblet cell carcinoma 2 trials
- Anal canal neuroendocrine neoplasm 1 trial Sub-types →
- Combined lung carcinoma 0 trials · 1 incl. sub-types Sub-types →
- Vulvar neuroendocrine carcinoma 0 trials Sub-types →
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Thyroid cancer 166 trials · 328 incl. sub-types
3 sub-types
- Thyroid gland carcinoma 41 trials · 237 incl. sub-types Sub-types →
- Thyroid lymphoma 0 trials Sub-types →
- Thyroid sarcoma 0 trials Sub-types →
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Thymus cancer 10 trials · 225 incl. sub-types
2 sub-types
- Thymus lymphoma 0 trials · 175 incl. sub-types Sub-types →
- Thymic carcinoma 41 trials · 44 incl. sub-types Sub-types →
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Adrenal gland cancer 16 trials · 62 incl. sub-types
3 sub-types
- Adrenal carcinoma 34 trials · 52 incl. sub-types Sub-types →
- Malignant tumor of adrenal cortex 0 trials · 42 incl. sub-types Sub-types →
- Adrenal medulla cancer 0 trials · 11 incl. sub-types Sub-types →
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Pineal gland cancer 0 trials · 19 incl. sub-types
3 sub-types
- Pineoblastoma 15 trials Sub-types →
- Malignant pineal area germ cell neoplasm 2 trials · 3 incl. sub-types Sub-types →
- Pineal gland astrocytoma 1 trial
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Malignant tumor of parathyroid gland 2 trials · 6 incl. sub-types
1 sub-type
- Parathyroid gland carcinoma 4 trials
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Pituitary cancer 2 trials · 4 incl. sub-types
4 sub-types
- Pituitary adenocarcinoma 3 trials Sub-types →
- Growth hormone-producing pituitary gland carcinoma 0 trials
- Pituicytoma 0 trials
- Pituitary blastoma 0 trials
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Ovarian neuroendocrine neoplasm 0 trials · 2 incl. sub-types
2 sub-types
- Ovarian small cell carcinoma 1 trial · 2 incl. sub-types Sub-types →
- Ovarian large-cell neuroendocrine carcinoma 0 trials
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Malignant carotid body paraganglioma 0 trials
Most studied deeper sub-types
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New drug combo aims to control Hard-to-Treat cancers
Disease control OngoingThis study tests a combination of two drugs, selumetinib and olaparib, in people with advanced or recurrent solid tumors (including ovarian, endometrial, breast, and others) that have specific genetic changes or have stopped responding to similar treatments. The first phase finds…
Phase 1 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 12:08 UTC
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New pill shows promise against Hard-to-Treat RET-Driven cancers
Disease control OngoingThis study tests an oral drug called selpercatinib in people with advanced solid tumors that have RET gene alterations, including certain lung, thyroid, and colon cancers. The goal is to find the best dose and see if the drug can shrink tumors. About 857 participants are enrolled…
Phase 1/2 • Sponsor: Eli Lilly and Company • Aim: Disease control
Last updated Jun 27, 2026 12:08 UTC
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Bacteria bombs target stubborn tumors in new cancer combo trial
Disease control OngoingThis study tests a special bacteria (Clostridium novyi-NT) injected directly into tumors, combined with the immunotherapy drug pembrolizumab, for people with advanced solid tumors that haven't responded to standard treatments. The bacteria are designed to break down tumor cells f…
Phase 1 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 12:07 UTC
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New oral drug shows promise for kids with rare RET-Driven cancers
Disease control OngoingThis study tests an oral drug called selpercatinib (LOXO-292) in children with advanced solid or brain tumors that have a specific RET gene change. The trial has two parts: first finding a safe dose, then measuring how many children's tumors shrink. About 36 children whose cancer…
Phase 1/2 • Sponsor: Eli Lilly and Company • Aim: Disease control
Last updated Jun 27, 2026 08:09 UTC
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Magic mushroom therapy offers hope for advanced cancer patients
Symptom relief OngoingThis study tests whether a single high dose of psilocybin (the active ingredient in magic mushrooms) combined with specialized talk therapy can help people with advanced cancer feel less anxious and more at peace. Fifteen adults with stage IV cancer will receive the treatment and…
Phase 2 • Sponsor: University Health Network, Toronto • Aim: Symptom relief
Last updated Jun 27, 2026 14:01 UTC