Bacteria bombs target stubborn tumors in new cancer combo trial
NCT ID NCT03435952
First seen Nov 01, 2025 · Last updated Jun 17, 2026 · Updated 32 times
Summary
This study tests a special bacteria (Clostridium novyi-NT) injected directly into tumors, combined with the immunotherapy drug pembrolizumab, for people with advanced solid tumors that haven't responded to standard treatments. The bacteria are designed to break down tumor cells from the inside, while pembrolizumab helps the immune system attack the cancer. The main goal is to find the safest dose of the bacteria and see if the combination can control the disease. Up to 18 participants will be treated at MD Anderson Cancer Center.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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University of Texas MD Anderson Cancer Center
Houston, Texas, 77030, United States
Conditions
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