Male reproductive system disorder
MONDO:0003150A disease involving the male reproductive system.
Also known as: Male reproductive system disease, Male reproductive system disorder, disease of male reproductive system, disease or disorder of male reproductive system, disorder of Male reproductive system, disorder of male reproductive system, male reproductive disease, male reproductive system disease
2836 clinical trials for this condition and its sub-types, 11 tagged with Male reproductive system disorder itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Male reproductive system disorder
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Prostate disorder 16 trials · 2,448 incl. sub-types
5 sub-types
- Prostate neoplasm 126 trials · 2,233 incl. sub-types Sub-types →
- Benign prostatic hyperplasia 226 trials
- Prostatitis 4 trials · 15 incl. sub-types Sub-types →
- Prostate calculus 0 trials
- Prostatic cyst 0 trials
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Male reproductive system neoplasm 1 trial · 2,378 incl. sub-types
6 sub-types
- Male reproductive organ cancer 22 trials · 2,355 incl. sub-types Sub-types →
- Neoplasm of testis 4 trials · 101 incl. sub-types Sub-types →
- Penile neoplasm 30 trials · 65 incl. sub-types Sub-types →
- Scrotum neoplasm 1 trial · 2 incl. sub-types Sub-types →
- Epididymal neoplasm 0 trials Sub-types →
- Lipoma of spermatic cord 0 trials
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Penile disorder 3 trials · 195 incl. sub-types
7 sub-types
- Erectile dysfunction 122 trials · 126 incl. sub-types Sub-types →
- Penile neoplasm 30 trials · 65 incl. sub-types Sub-types →
- Phimosis 2 trials Sub-types →
- Balanitis 0 trials · 1 incl. sub-types Sub-types →
- Leukoplakia of penis 0 trials
- Posthitis 0 trials Sub-types →
- Vascular disorder of penis 0 trials
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Testicular disorder 2 trials · 111 incl. sub-types
8 sub-types
- Neoplasm of testis 4 trials · 101 incl. sub-types Sub-types →
- Spermatic cord torsion 7 trials
- Orchitis 1 trial · 2 incl. sub-types Sub-types →
- Atrophy of testis 1 trial
- Acquired testicular failure 0 trials
- Chylocele of tunica vaginalis 0 trials
- Testicular dysgenesis syndrome 0 trials
- Testicular infarct 0 trials
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Male infertility 74 trials · 92 incl. sub-types
8 sub-types
- Azoospermia 25 trials
- Oligospermia 20 trials
- Spermatogenic failure 1 trial · 12 incl. sub-types Sub-types →
- Oligoasthenoteratozoospermia 11 trials
- Partial chromosome Y deletion 0 trials · 5 incl. sub-types Sub-types →
- Male infertility with teratozoospermia due to single gene mutation 0 trials · 1 incl. sub-types Sub-types →
- Infertility due to extratesticular cause 0 trials
- Male infertility due to acephalic spermatozoa 0 trials
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Scrotal disorder 2 trials · 19 incl. sub-types
2 sub-types
- Varicocele 15 trials
- Scrotum neoplasm 1 trial · 2 incl. sub-types Sub-types →
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Cryptorchidism 14 trials
1 sub-type
- Arroyo Garcia Cimadevilla syndrome 0 trials
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Hydrocele 6 trials
1 sub-type
- Infected hydrocele 0 trials
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Epididymitis 2 trials
2 sub-types
- Epididymo-orchitis 0 trials Sub-types →
- Tuberculous epididymitis 0 trials
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Fournier gangrene 2 trials
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3 sub-types
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Isolated micropenis 1 trial
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Spermatocele 1 trial
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6 sub-types
- Benign neoplasm of epididymis 0 trials Sub-types →
- Benign neoplasm of penis 0 trials
- Benign neoplasm of prostate 0 trials Sub-types →
- Benign neoplasm of scrotum 0 trials Sub-types →
- Benign neoplasm of testis 0 trials Sub-types →
- Lipoma of spermatic cord 0 trials
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Congenital agenesis of the scrotum 0 trials
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Congenital megaprepuce 0 trials
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Diphallia 0 trials
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Epididymis disease 0 trials
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Male genital organ stricture 0 trials
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Male genital organ vascular disease 0 trials
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Male genital tuberculosis 0 trials
1 sub-type
- Tuberculous epididymitis 0 trials
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Penoscrotal transposition 0 trials
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Posterior hypospadias 0 trials
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Postorgasmic illness syndrome 0 trials
Most studied deeper sub-types
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New hope for tough prostate cancer: first human trial of VIR-5500 begins
Disease control Recruiting nowThis early-stage study tests a new drug called VIR-5500 in people with advanced prostate cancer that has stopped responding to hormone treatment. The main goals are to check the drug's safety and find the right dose, while also seeing if it can shrink tumors or lower PSA levels. …
Phase 1 • Sponsor: Astellas Pharma Global Development, Inc. • Aim: Disease control
Last updated Sep 12, 2026 00:00 UTC
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New pill HLD-0915 takes on tough prostate cancer
Disease control Recruiting nowThis study tests an experimental oral drug called HLD-0915 in men with metastatic prostate cancer that has worsened after other treatments. The trial has two phases: Phase 1 checks safety and the best dose, while Phase 2 looks at how well it controls the cancer. About 190 men wil…
Phase 1/2 • Sponsor: Janssen Research & Development, LLC • Aim: Disease control
Last updated Sep 02, 2026 00:00 UTC
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New drug duo takes on Hard-to-Treat prostate cancer
Disease control Recruiting nowThis study tests two drugs—gedatolisib and darolutamide—together in men with metastatic castration-resistant prostate cancer (mCRPC), a type that has spread and no longer responds to standard hormone therapy. The first part finds the safest dose, and the second checks if the comb…
Phase 1/2 • Sponsor: Celcuity Inc • Aim: Disease control
Last updated Jun 27, 2026 12:06 UTC
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Writing away worry: study tests journaling for parents of kids with DSD
Symptom relief Recruiting nowThis study tests whether a guided journaling program can reduce anxiety in parents of children with urogenital conditions like differences of sex development (DSD) or hypospadias. Twenty parents will complete five writing prompts over several weeks and then share their experience…
Sponsor: Sarah Schlegel • Aim: Symptom relief
Last updated Jun 27, 2026 12:34 UTC