Male breast carcinoma

This phase III trial is investigating whether adding lapatinib to the standard combination of paclitaxel and trastuzumab before surgery can improve outcomes for patients with HER2-positive stage II or III breast cancer. The study aims to see if the three-drug regimen leads to a h…

This phase 2 trial tested whether adding carboplatin and/or bevacizumab to standard chemotherapy before surgery helps shrink tumors in people with a hard-to-treat type of breast cancer (hormone receptor-poor, HER2-negative, including triple-negative). 454 participants received we…

This early-phase study tested a vaccine made from patients' own immune cells to target HER2-positive breast cancer. 31 participants with stage II or III breast cancer received the vaccine alongside standard chemotherapy before surgery. The goal was to see if the vaccine could boo…

This study tested a new immune-boosting treatment called IRX-2 in 16 people with early stage breast cancer. The goal was to see if giving IRX-2 before chemotherapy is safe and helps the immune system fight the tumor. The treatment was given before surgery, and researchers looked …

This early-phase trial tested a precise, high-dose radiation technique called stereotactic body radiotherapy (SBRT) in 42 patients with breast, lung, or prostate cancer that had spread to several places in the body. The main goal was to find the safest dose and check for side eff…

This study collected information from 93 men who have had breast cancer. Participants filled out a questionnaire about their life, work, family, and health history. The goal is to find patterns that might help explain why some men develop breast cancer. No treatments or drugs wer…

Breast cancer in men is rare, making up only 1% of cases, and most research has focused on women. This study aims to develop a questionnaire specifically for men with breast cancer to measure their quality of life. Researchers interviewed 65 patients and healthcare professionals …

This completed study looked at why certain breast cancer drugs stop working over time. Researchers collected tumor samples from 269 patients to study genetic changes that might cause resistance. The goal was to better understand these mechanisms so that future treatments can be i…

This study looked at the different types of cells inside breast tumors to better understand how they affect treatment response. Researchers used advanced molecular tools to analyze samples from 145 people with breast cancer. The goal was to gather knowledge that could lead to bet…