Macular holes
MONDO:0006843A hole in the macula of the retina.
Also known as: macular hole
31 clinical trials for this condition and its sub-types, 19 tagged with Macular holes itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Part of
-
Amniotic gel could patch macular holes without complex surgery
Disease control Recruiting nowThis study tests a new gel made from donated amniotic membrane to treat large macular holes, a condition that blurs central vision. The gel is injected into the eye during surgery to help close the hole. Researchers will compare this method to the standard flap technique in 26 ad…
Sponsor: Walailak University • Aim: Disease control
Last updated Sep 11, 2026 00:00 UTC
-
Eye surgery showdown: which technique best fixes macular holes?
Disease control Recruiting nowThis pilot study compares two surgical techniques for closing idiopathic macular holes: using a Tenon capsule graft versus the standard internal limiting membrane (ILM) flap. Twenty participants will undergo vitrectomy and be assigned to one of the two groups. The study will meas…
Sponsor: Ain Shams University • Aim: Disease control
Last updated Jun 27, 2026 13:04 UTC
-
Which surgery best fixes macular holes? new trial aims to find out
Disease control Recruiting nowThis study is testing ten different surgical methods to repair full-thickness macular holes, a condition that blurs central vision. 120 adults will be randomly assigned to one technique during vitrectomy surgery. The main goal is to see which method closes the hole most often and…
Sponsor: Kazakh Eye Research Institute • Aim: Disease control
Last updated Jun 27, 2026 13:00 UTC
-
Patch of your own eye tissue may fix stubborn vision holes
Disease control Recruiting nowThis study tests a new surgical technique for people with macular holes that didn't close after standard treatment. Surgeons take a small piece of the patient's own eye tissue (Tenon's capsule) and use it as a patch to plug the hole. Twenty participants will be followed for 3 mon…
Sponsor: Benha University • Aim: Disease control
Last updated Jun 27, 2026 08:08 UTC
-
New eye implant could replace drops after retina surgery
Symptom relief Recruiting nowThis study tests a tiny gel-like insert placed in the tear duct that releases dexamethasone, a steroid, to reduce pain and swelling after vitreoretinal surgery. It compares the insert to standard steroid eye drops in 30 adults undergoing surgery for conditions like macular holes …
Phase 4 • Sponsor: The Cleveland Clinic • Aim: Symptom relief
Last updated Jul 31, 2026 00:00 UTC
-
No bubble needed? new eye surgery could change macular hole repair
Symptom relief Recruiting nowThis study compares two surgeries for macular holes, a common cause of vision loss. The standard method uses a gas bubble to help the hole close, but the new technique skips the bubble. Researchers want to see if the new method works just as well and makes recovery easier for pat…
Sponsor: Chinese University of Hong Kong • Aim: Symptom relief
Last updated Jun 27, 2026 07:52 UTC
-
Which eye surgery machine is faster? new study puts UNITY VCS to the test
Knowledge-focused Recruiting nowThis study compares two surgical systems used for combined cataract and vitrectomy eye surgeries. The UNITY VCS system is being tested against the CONSTELLATION system to see which one surgeons find more efficient in real-world operating rooms. About 180 adults needing combined e…
Sponsor: Alcon Research • Aim: Knowledge-focused
Last updated Aug 15, 2026 00:00 UTC
-
New microscope camera could make eye surgery safer and more precise
Knowledge-focused Recruiting nowThis study tests a special microscope that takes live 3D images inside the eye during surgery. It aims to help surgeons see better when treating conditions like retinal detachment, macular holes, and cataracts. About 262 people will take part, including healthy volunteers and sur…
Sponsor: Duke University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:54 UTC