Machado-Joseph disease type 3

MONDO:0017176

Machado-Joseph disease type 3 is a subtype of Machado-Joseph disease (SCA3/MJD) of milder severity characterized by late onset, slower progression, and peripheral amyotrophy.

Also known as: SCA3, Machado type, azorean disease, type iii, spinocerebellar ataxia type 3, Machado type

21 clinical trials for this condition and its sub-types, 2 tagged with Machado-Joseph disease type 3 itself.

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Where it sits in the disease tree

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↑ Machado-Joseph disease (11)

Including sub-types (21) Tagged with Machado-Joseph disease type 3 (2)

Not yet recruiting 1 Completed 1

Hope for ataxia: experimental drug shows promise in Late-Stage trial

Disease control Completed

This study tested a drug called troriluzole in 141 adults with spinocerebellar ataxia, a rare disease that affects balance and coordination. Participants took either the drug or a placebo daily for 8 weeks. The main goal was to see if troriluzole could improve symptoms like walki…

Phase 2/3 • Sponsor: Biohaven Pharmaceuticals, Inc. • Aim: Disease control

Last updated Jun 27, 2026 07:53 UTC

Machado-Joseph disease type 3

Where it sits in the disease tree

Hope for ataxia: experimental drug shows promise in Late-Stage trial