Lobular breast carcinoma in situ
MONDO:0006270A non-invasive adenocarcinoma of the breast characterized by a proliferation of monomorphic cells completely filling the lumina. The overall lobular architecture is preserved. It is frequently multifocal (90% in some series) and bilateral. It seldom becomes invasive; however there is an increased risk of infiltrating ductal adenocarcinoma.
Also known as: LCIS, lobular Ca in situ of breast, lobular Ca in situ of the breast, lobular breast carcinoma in situ, lobular carcinoma in situ, lobular carcinoma in situ (LCIS), lobular carcinoma in situ of breast, lobular carcinoma in situ of the breast
2840 clinical trials for this condition and its sub-types, 27 tagged with Lobular breast carcinoma in situ itself.
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New hope for chemo-resistant breast cancer? trial tests immune-boosting drug
Disease control Stopped earlyThis study looked at whether the drug abemaciclib could help people with triple negative breast cancer that didn't respond to standard chemotherapy. The goal was to see if the drug could change the tumor's immune environment to make it more attackable by the body's defenses. The …
Phase 2 • Sponsor: Mayo Clinic • Aim: Disease control
Last updated Jun 27, 2026 07:57 UTC
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Breast cancer prevention study halted: tamoxifen pill vs. gel tested
Prevention Stopped earlyThis study aimed to see if a tamoxifen skin gel could work as well as the pill to lower breast cancer risk in women with certain high-risk breast conditions. The trial enrolled 65 women and compared short-term changes in breast tissue. However, the study was terminated early, so …
Phase 2 • Sponsor: Mayo Clinic • Aim: Prevention
Last updated Sep 03, 2026 00:00 UTC
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Genetic test aims to improve breast cancer decisions for black and hispanic women
Knowledge-focused Stopped earlyThis study looked at whether adding a polygenic risk score (a genetic test) to standard breast cancer risk tools helps African American and Hispanic women make better decisions about screening and prevention. Researchers enrolled 19 women at higher risk for breast cancer. The stu…
Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:28 UTC