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Lewis-Sumner syndrome

MONDO:0018826

A rare acquired demyelinating polyneuropathy characterized by asymmetrical distal weakness of the upper or lower extremities and motor dysfunction with adult onset. It is considered to be a variant of chronic inflammatory demyelinating polyneuropathy.

Also known as: MADSAM, multifocal acquired demyelinating sensory and motor neuropathy

9 clinical trials for this condition and its sub-types, 0 tagged with Lewis-Sumner syndrome itself.

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Where it sits in the disease tree

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Part of

↑ Chronic inflammatory demyelinating polyradiculoneuropathy (62)

Including sub-types (9) Tagged with Lewis-Sumner syndrome (0)

Trials to join now! 4 Not yet recruiting 1 Not yet finished but already full! 1 Completed 2 Terminated 1

Can wearable sensors and walking tests reliably track nerve damage?

Knowledge-focused Ongoing

Researchers are checking whether tests of muscle strength, walking, balance, and fine motor skills give consistent results in people with polyneuropathy. About 520 adults with various forms of nerve damage, plus healthy volunteers, take part. Participants complete physical tests,…

Sponsor: Rigshospitalet, Denmark • Aim: Knowledge-focused

Last updated Sep 17, 2026 00:00 UTC

Lewis-Sumner syndrome

Where it sits in the disease tree

Can wearable sensors and walking tests reliably track nerve damage?